Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System
文献类型：期刊论文
| 作者 | Gui, Wanyuan1; Wang, Wenqian1; Jiao, Xiangyu1; Chen, Lifeng2; Wen, Yongqiang1; Zhang, Xueji1 |
| 刊名 | CHEMPHYSCHEM
 |
| 出版日期 | 2015-02-23 |
| 卷号 | 16期号:3页码:607-613 |
| ISSN号 | 1439-4235 |
| 关键词 | Drug Delivery Mesoporous Materials Nanostructures Sensors Sol-gel Processes |
| DOI | 10.1002/cphc.201402732 |
| 英文摘要 | A pH-controlled delivery system based on mesoporous silica nanoparticles (MSNs) was constructed for dual-cargo selective release. To achieve a better controlled-release effect, a modified sol-gel method was employed to obtain MSNs with tunable particle and pore sizes. The systems selectively released different kinds of cargo when stimulated by different pH values. At the lower pH value (pH 2.0) only one kind of cargo was released from the MSNs, whereas at a higher pH value (pH 7.0) only the other kind of cargo was released from the MSNs. The multi-cargo delivery system has brought the concept of selective release to new advances in the field of functional nanodevices and allows more accurate and controllable delivery of specific cargoes, which is expected to have promising applications in nanomedicine. |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000349964000015 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/53331]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wen, Yongqiang |
| 作者单位 | 1.Univ Sci & Technol Beijing, Dept Chem & Biol Engn, Beijing 100083, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gui, Wanyuan,Wang, Wenqian,Jiao, Xiangyu,et al. Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System[J]. CHEMPHYSCHEM,2015,16(3):607-613. |
| APA | Gui, Wanyuan,Wang, Wenqian,Jiao, Xiangyu,Chen, Lifeng,Wen, Yongqiang,&Zhang, Xueji.(2015).Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System.CHEMPHYSCHEM,16(3),607-613. |
| MLA | Gui, Wanyuan,et al."Dual-Cargo Selectively Controlled Release Based on a pH-Responsive Mesoporous Silica System".CHEMPHYSCHEM 16.3(2015):607-613. |
入库方式： OAI收割
来源：化学研究所
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