No king without a crown - impact of the nanomaterial-protein corona on nanobiomedicine
文献类型：期刊论文
| 作者 | Docter, Dominic1; Strieth, Sebastian1; Westmeier, Dana1; Hayden, Oliver2; Gao, Mingyuan3; Knauer, Shirley K.4; Stauber, Roland H.1 |
| 刊名 | NANOMEDICINE
 |
| 出版日期 | 2015 |
| 卷号 | 10期号:3页码:503-519 |
| 关键词 | Bioinformatics Blood System Colloidal Chemistry Label-free Quantification Mass Spectrometry Nanomaterials Nanomedicine Nanotoxicology Proteomics |
| ISSN号 | 1743-5889 |
| DOI | 10.2217/nnm.14.184 |
| 英文摘要 | Besides the wide use of nanomaterials in technical products, their application spectrum in biotechnology and biomedicine is steadily increasing. Whereas the physico-chemical properties and behavior of nanomaterials can be engineered and characterized accurately under idealized conditions, this is no longer the case in complex physiological environments. In biological fluids, proteins rapidly bind to nanomaterials forming the protein corona, critically affecting the nanomaterials' biological identity. As the corona impacts in vitro and/or in vivo nanomaterial applications, we here review the concept of the protein corona and its analytical dissection. We comment on how corona signatures may be linked to effects at the nano-bio interface and conclude how such knowledge is offering novel opportunities for improved nanomedicine. |
| 语种 | 英语 |
| WOS记录号 | WOS:000350246600013 |
| 出版者 | FUTURE MEDICINE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/53371]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Docter, Dominic |
| 作者单位 | 1.Univ Med Ctr Mainz, Dept Nanobiomed, ENT, D-55101 Mainz, Germany 2.Siemens AG, Corp Technol, D-91058 Erlangen, Germany 3.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China 4.Univ Duisburg Essen, CENIDE, Inst Mol Biol, D-45117 Essen, Germany |
| 推荐引用方式 GB/T 7714 | Docter, Dominic,Strieth, Sebastian,Westmeier, Dana,et al. No king without a crown - impact of the nanomaterial-protein corona on nanobiomedicine[J]. NANOMEDICINE,2015,10(3):503-519. |
| APA | Docter, Dominic.,Strieth, Sebastian.,Westmeier, Dana.,Hayden, Oliver.,Gao, Mingyuan.,...&Stauber, Roland H..(2015).No king without a crown - impact of the nanomaterial-protein corona on nanobiomedicine.NANOMEDICINE,10(3),503-519. |
| MLA | Docter, Dominic,et al."No king without a crown - impact of the nanomaterial-protein corona on nanobiomedicine".NANOMEDICINE 10.3(2015):503-519. |
入库方式： OAI收割
来源：化学研究所
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