Fluorescence Turn-On Chemosensor for Highly Selective and Sensitive Detection and Bioimaging of Al3+ in Living Cells Based on Ion-Induced Aggregation
文献类型：期刊论文
| 作者 | Gui, Shilang1; Huang, Yanyan2; Hu, Fang2; Jin, Yulong2; Zhang, Guanxin2; Yan, Liushui1; Zhang, Deqing2; Zhao, Rui2 |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2015-02-03 |
| 卷号 | 87期号:3页码:1470-1474 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/ac504153c |
| 英文摘要 | Herein, a new fluorescence turn-on chemosensor 2-(4-(1,2,2-triphenylvinyl)phenoxy)acetic acid (TPE-COOH) specific for Al3+ was presented by combining the aggregation-induced-emission (AIE) effect of tertaphenylethylene and the complexation capability of carboxyl. The introduction of carboxylic group provides the probe with good water-solubility which is important for analyzing biological samples. The recognition toward Al3+ induced the molecular aggregation and activated the blue fluorescence of the TPE core. The high selectivity of the probe was demonstrated by discriminating Al3+ over a variety of metal ions in a complex mixture. A detection limit down to 21.6 nM was determined for Al3+ quantitation. Furthermore, benefiting from its good water solubility and biocompatibility, imaging detection and real-time monitoring of Al3+ in living HeLa cells were successfully achieved. The AIE effect of the probe enables high signal-to-noise ratio for bioimaging even without multiple washing steps. These superiorities make this probe a great potential for the functional study and analysis of Al3+ in complex biosystems. |
| 语种 | 英语 |
| WOS记录号 | WOS:000349059000007 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/53503]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Yan, Liushui |
| 作者单位 | 1.Nanchang Hangkong Univ, Sch Environm & Chem Engn, Nanchang 330063, Peoples R China 2.Chinese Acad Sci, Beijing Natl Lab Mol Sci, CAS Key Labs Analyt Chem Living Biosyst & Organ S, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gui, Shilang,Huang, Yanyan,Hu, Fang,et al. Fluorescence Turn-On Chemosensor for Highly Selective and Sensitive Detection and Bioimaging of Al3+ in Living Cells Based on Ion-Induced Aggregation[J]. ANALYTICAL CHEMISTRY,2015,87(3):1470-1474. |
| APA | Gui, Shilang.,Huang, Yanyan.,Hu, Fang.,Jin, Yulong.,Zhang, Guanxin.,...&Zhao, Rui.(2015).Fluorescence Turn-On Chemosensor for Highly Selective and Sensitive Detection and Bioimaging of Al3+ in Living Cells Based on Ion-Induced Aggregation.ANALYTICAL CHEMISTRY,87(3),1470-1474. |
| MLA | Gui, Shilang,et al."Fluorescence Turn-On Chemosensor for Highly Selective and Sensitive Detection and Bioimaging of Al3+ in Living Cells Based on Ion-Induced Aggregation".ANALYTICAL CHEMISTRY 87.3(2015):1470-1474. |
入库方式： OAI收割
来源：化学研究所
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