Rapid detection of polyhydroxylated alkaloids in mulberry using leaf spray mass spectrometry
文献类型：期刊论文
| 作者 | Zhang, Ning1,2; Li, Yafeng1,2; Zhou, Yueming1,2; Hou, Jian1,2; He, Qing1,2; Hu, Xiang-Guo2,3; Jia, Yue-Mei2,3; Yu, Chu-Yi2,3; Nie, Zongxiu1,2,4 |
| 刊名 | ANALYTICAL METHODS
 |
| 出版日期 | 2013 |
| 卷号 | 5期号:10页码:2455-2460 |
| ISSN号 | 1759-9660 |
| DOI | 10.1039/c3ay00018d |
| 英文摘要 | Polyhydroxylated alkaloids, or alkaloidal iminosugars, which exhibit potent bioactivity as glycosidase inhibitors, can be used as potential therapeutic agents or as tools for probing into biological recognition processes. Mulberry has aroused considerable research interest in recent decades as it is rich in polyhydroxylated alkaloids, in particular it is a major natural source of 1-deoxyjirimycin ( DNJ). In the present work, we achieved the rapid and direct detection of polyhydroxylated alkaloids in mulberry using leaf spray mass spectrometry. By semi-quantitative analysis, the relative content of DNJ in different plant materials from mulberry trees was recorded and the experimental results provided us an insight into the distribution of DNJ in mulberry, which can be instructive and informative for the practical production of functional or medical mulberry food. In addition, thanks to its fast, simple and high throughput characteristics, the leaf spray method exhibits promising application in the rapid screening of lead compounds from natural plants during drug development. |
| 语种 | 英语 |
| WOS记录号 | WOS:000318314700003 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/53647]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Nie, Zongxiu |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China 2.Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Inst Chem, CAS Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China 4.Beijing Ctr Mass Spectrometry, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Ning,Li, Yafeng,Zhou, Yueming,et al. Rapid detection of polyhydroxylated alkaloids in mulberry using leaf spray mass spectrometry[J]. ANALYTICAL METHODS,2013,5(10):2455-2460. |
| APA | Zhang, Ning.,Li, Yafeng.,Zhou, Yueming.,Hou, Jian.,He, Qing.,...&Nie, Zongxiu.(2013).Rapid detection of polyhydroxylated alkaloids in mulberry using leaf spray mass spectrometry.ANALYTICAL METHODS,5(10),2455-2460. |
| MLA | Zhang, Ning,et al."Rapid detection of polyhydroxylated alkaloids in mulberry using leaf spray mass spectrometry".ANALYTICAL METHODS 5.10(2013):2455-2460. |
入库方式： OAI收割
来源：化学研究所
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