One-step packing of anti-voltage photonic crystals into microfluidic channels for ultra-fast separation of amino acids and peptides
文献类型：期刊论文
| 作者 | Liao, Tao1; Guo, Zhengpeng1; Li, Jincheng1; Liu, Meirong1; Chen, Yi1,2 |
| 刊名 | LAB ON A CHIP
 |
| 出版日期 | 2013 |
| 卷号 | 13期号:4页码:706-713 |
| ISSN号 | 1473-0197 |
| DOI | 10.1039/c2lc40720e |
| 英文摘要 | Packing of stable and crack-free photonic crystals (PCs) into micro channels is a prerequisite for ideal separation, but often takes several days and many steps, including assembly and immobilization. This work was dedicated to finding a fast, one-step solution. Simply by heating and blowing away the vapor, the packing of silica PCs into micro channels by classic evaporation-induced assembly was greatly accelerated and could unite the immobilization into one step. An apt method was thus established, which was able to pack 2 cm PCs into microfluidic channels in 15 min, saving a lot of time. The packed PCs showed no evident cracks along the borders of their continuous domain, therefore they are capable of withstanding an antielectrical field at 2000 V cm(-1) for 5 h and storage in water for 2 months. This enables ultra-fast separation of amino acids along a 2.5 mm PC in 4 s, and peptides along a 10 mm PC in 12 s. The separation was highly efficient and reproducible, with a 300 nm plate height and 0.24%-0.35% relative standard deviation of migration time. This one-step approach is extendable to other gelling particles, and the resulted stable, crack-free PCs would have large potential in ultra-fast separation of other analytes. |
| 语种 | 英语 |
| WOS记录号 | WOS:000313971300026 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/53747]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Chen, Yi |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing 100864, Peoples R China 2.Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liao, Tao,Guo, Zhengpeng,Li, Jincheng,et al. One-step packing of anti-voltage photonic crystals into microfluidic channels for ultra-fast separation of amino acids and peptides[J]. LAB ON A CHIP,2013,13(4):706-713. |
| APA | Liao, Tao,Guo, Zhengpeng,Li, Jincheng,Liu, Meirong,&Chen, Yi.(2013).One-step packing of anti-voltage photonic crystals into microfluidic channels for ultra-fast separation of amino acids and peptides.LAB ON A CHIP,13(4),706-713. |
| MLA | Liao, Tao,et al."One-step packing of anti-voltage photonic crystals into microfluidic channels for ultra-fast separation of amino acids and peptides".LAB ON A CHIP 13.4(2013):706-713. |
入库方式： OAI收割
来源：化学研究所
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