Dopamine-Modified Cationic Conjugated Polymer as a New Platform for pH Sensing and Autophagy Imaging
文献类型：期刊论文
| 作者 | Wen, Quanshan; Liu, Libing; Yang, Qiong; Lv, Fengting; Wang, Shu |
| 刊名 | ADVANCED FUNCTIONAL MATERIALS
 |
| 出版日期 | 2013-02-11 |
| 卷号 | 23期号:6页码:764-769 |
| 关键词 | Conjugated Polymers Dopamine Ph Sensing Autophagy Imaging |
| ISSN号 | 1616-301X |
| DOI | 10.1002/adfm.201202132 |
| 英文摘要 | A dopamine-modified conjugated polymer PFPDA is synthesized and characterized. At low pH, dopamine exists in its hydroquinone form and lacks the ability to quench fluorescence. At high pH, the proportion of the quinone form of dopamine increases due to its autooxidation, and efficient intramolecular electron transfer from the polymer main chain to quinone occurs, resulting in the quenching of the fluorescence of PFPDA. Thus, PFPDA exhibits a fluorescence turn-on response at low pH. PFPDA possesses excellent photostability and exhibits no cytotoxicity, which makes it a good fluorescent material for pH sensing and cell imaging. A light-induced hydroxyl anion emitter, MGCB, is also used to change the pH of the solution and thus regulate the fluorescence of PFPDA via remote control under light irradiation. Because the cytoplasm becomes acidic when cell autophagy occurs, PFPDA can also be used for autophagy imaging of HeLa cells with good selectivity. |
| 语种 | 英语 |
| WOS记录号 | WOS:000314924900013 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/53757]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wen, Quanshan |
| 作者单位 | Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Organ Solids, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wen, Quanshan,Liu, Libing,Yang, Qiong,et al. Dopamine-Modified Cationic Conjugated Polymer as a New Platform for pH Sensing and Autophagy Imaging[J]. ADVANCED FUNCTIONAL MATERIALS,2013,23(6):764-769. |
| APA | Wen, Quanshan,Liu, Libing,Yang, Qiong,Lv, Fengting,&Wang, Shu.(2013).Dopamine-Modified Cationic Conjugated Polymer as a New Platform for pH Sensing and Autophagy Imaging.ADVANCED FUNCTIONAL MATERIALS,23(6),764-769. |
| MLA | Wen, Quanshan,et al."Dopamine-Modified Cationic Conjugated Polymer as a New Platform for pH Sensing and Autophagy Imaging".ADVANCED FUNCTIONAL MATERIALS 23.6(2013):764-769. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。