Conformation-specific Self-assembly of Thermo-responsive Poly(ethylene glycol)-b-polypeptide Diblock Copolymer
文献类型：期刊论文
| 作者 | Shen, Junyang1,2; Chen, Chongyi3; Fu, Wenxin3; Shi, Linqi1,2; Li, Zhibo3 |
| 刊名 | LANGMUIR
 |
| 出版日期 | 2013-05-28 |
| 卷号 | 29期号:21页码:6271-6278 |
| ISSN号 | 0743-7463 |
| DOI | 10.1021/ka401095s |
| 英文摘要 | Poly(ethylene glycol)-block-poly(gamma-(2-methoxyethoxy)esteryl-L-glutamate) (PEG-b-poly-L-EG(2)Glu) was synthesized via ring-opening polymerization (ROP) of L-EG(2)Glu N-carboxyanhydride (NCA) using PEG-NH2 as macroinitiator. This diblock contained a thermo-responsive poly-L-EG(2)Glu block, which adopted primarily helical conformation in pristine aqueous solution. We found that PEG-bpoly-L-EG(2)Glu diblock can display two levels of self-assembly behaviors associated with hydrophobic interactions and conformation specific reassembly, respectively. Upon temperature increase, the PEG-b-poly-L-EG(2)Glu diblock formed wormlike micelles, in which the poly-L-EG(2)Glu formed the micelle core and maintained helical conformation. However, extension of thermal annealing time drove the secondary structure transformation of the poly-L-EG(2)Glu block from helical conformation to beta-sheet, which accounted for an assembly structure transition from wormlike micelles to nanoribbons. The critical factor was that poly-L-EG(2)Glu block can undergo thermo-induced hydrophobicity and conformation transformation, which offered an additional parameter to tune the nature of molecular interactions, i.e intermolecular versus intramolecular hydrogen bonding interactions. The corresponding conformation and assembly structure changes were characterized using FTIR and electron microscopy, respectively. |
| 语种 | 英语 |
| WOS记录号 | WOS:000319796300008 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/53933]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Shi, Linqi |
| 作者单位 | 1.Nankai Univ, Key Lab Funct Polymer Mat, Minist Educ, Tianjin 300071, Peoples R China 2.Nankai Univ, Inst Polymer Chem, Tianjin 300071, Peoples R China 3.Chinese Acad Sci, BNLMS, Lab Polymer Phys & Chem, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shen, Junyang,Chen, Chongyi,Fu, Wenxin,et al. Conformation-specific Self-assembly of Thermo-responsive Poly(ethylene glycol)-b-polypeptide Diblock Copolymer[J]. LANGMUIR,2013,29(21):6271-6278. |
| APA | Shen, Junyang,Chen, Chongyi,Fu, Wenxin,Shi, Linqi,&Li, Zhibo.(2013).Conformation-specific Self-assembly of Thermo-responsive Poly(ethylene glycol)-b-polypeptide Diblock Copolymer.LANGMUIR,29(21),6271-6278. |
| MLA | Shen, Junyang,et al."Conformation-specific Self-assembly of Thermo-responsive Poly(ethylene glycol)-b-polypeptide Diblock Copolymer".LANGMUIR 29.21(2013):6271-6278. |
入库方式： OAI收割
来源：化学研究所
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