PEGylated nanoparticles of diperylene bisimides with high efficiency of O-1(2) generation
文献类型:期刊论文
作者 | Cui, Yi1; Wu, Yishi3; Liu, Yu1; Yang, Gaomai2; Liu, Lixin3; Fu, Hongbing3; Li, Zhibo1; Wang, Shu2; Wang, Zhaohui2; Chen, Yongming1 |
刊名 | DYES AND PIGMENTS
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出版日期 | 2013-04-01 |
卷号 | 97期号:1页码:129-133 |
关键词 | Click Coupling Reaction Diperylene Bisimide Peg-dipbi Photodynamic Therapy Phototoxicity Singlet Oxygen |
ISSN号 | 0143-7208 |
DOI | 10.1016/j.dyepig.2012.12.008 |
英文摘要 | Diperylene bisimide bearing poly(ethylene glycol) chains (PEG-diPBI) were synthesized using click coupling reaction between mono-azido terminated PEG(113) and bis-alkynyl functionalized diPBI. Then the PEG-diPBI self-assembled into micelles in water, which were characterized by cryo-TEM, UV-Vis spectrometry and fluorescence spectrometry. Furthermore, the PEG-diPBI was applied by continuous photolysis procedure, the result showed a broad absorption and very high efficiency of O-1(2) generation (Phi(Delta) = 0.66). Moreover, the uptake of PEG-diPBI particles by human bladder carcinoma EJ cells was observed by confocal laser scanning microscopy. Also, phototoxicity experiment result was applied to PEG-diPBI, and gave the result that it is worth to investigate the properties of PEG-diPBI particles for photodynamic therapy. (C) 2012 Elsevier Ltd. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000315608000019 |
出版者 | ELSEVIER SCI LTD |
源URL | [http://ir.iccas.ac.cn/handle/121111/53953] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Chen, Yongming |
作者单位 | 1.Chinese Acad Sci, Inst Chem, Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Inst Chem, Key Lab Organ Solids, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Inst Chem, Key Lab Photochem, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Cui, Yi,Wu, Yishi,Liu, Yu,et al. PEGylated nanoparticles of diperylene bisimides with high efficiency of O-1(2) generation[J]. DYES AND PIGMENTS,2013,97(1):129-133. |
APA | Cui, Yi.,Wu, Yishi.,Liu, Yu.,Yang, Gaomai.,Liu, Lixin.,...&Chen, Yongming.(2013).PEGylated nanoparticles of diperylene bisimides with high efficiency of O-1(2) generation.DYES AND PIGMENTS,97(1),129-133. |
MLA | Cui, Yi,et al."PEGylated nanoparticles of diperylene bisimides with high efficiency of O-1(2) generation".DYES AND PIGMENTS 97.1(2013):129-133. |
入库方式: OAI收割
来源:化学研究所
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