Polystyrene Spheres-Assisted Matrix-Assisted Laser Desorption Ionization Mass Spectrometry for Quantitative Analysis of Plasma Lysophosphatidylcholines
文献类型：期刊论文
| 作者 | Wei, Yanbo1,2; Li, Shumu3; Wang, Jingxia3; Shu, Chunying3; Liu, Jian'an2; Xiong, Shaoxiang2; Song, Jianwen4; Zhang, Junjie4; Zhao, Zhenwen1,2 |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2013-05-07 |
| 卷号 | 85期号:9页码:4729-4734 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/ac400452k |
| 英文摘要 | The quantitative analysis by matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) is a challenge due to the poor reproducibility originating from the heterogeneity of the matrix-analyte crystals. Polystyrene (PS) colloidal spheres have superior monodispersed property and can self-assemble to form photonic crystals. With the assistance of PS spheres, a uniform matrix-analyte cocrystal was constructed for the quantitative analysis of plasma lysophosphatidylcholines (LPCs). The matrix and the solvent in MALDI MS analysis were optimized, and the reproducibility and the accuracy were investigated in detail. This is the first report about the very simple method of PS spheres assisted MALDI MS for quantitative analysis, where it is believed that this approach will greatly expand the applications of MALDI MS. |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000318756100073 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/54059]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, Zhenwen |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Analyt Chem Living Biosyst, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Beijing Mass Spectrum Ctr, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Inst Chem, Key Lab Mol Nanostruct & Nanotechnol, Beijing 100190, Peoples R China 4.Beijing Normal Univ, Coll Life Sci, Key Lab Cell Proliferat & Regulat Biol, Minist Educ,Inst Cell Biol, Beijing 100875, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wei, Yanbo,Li, Shumu,Wang, Jingxia,et al. Polystyrene Spheres-Assisted Matrix-Assisted Laser Desorption Ionization Mass Spectrometry for Quantitative Analysis of Plasma Lysophosphatidylcholines[J]. ANALYTICAL CHEMISTRY,2013,85(9):4729-4734. |
| APA | Wei, Yanbo.,Li, Shumu.,Wang, Jingxia.,Shu, Chunying.,Liu, Jian'an.,...&Zhao, Zhenwen.(2013).Polystyrene Spheres-Assisted Matrix-Assisted Laser Desorption Ionization Mass Spectrometry for Quantitative Analysis of Plasma Lysophosphatidylcholines.ANALYTICAL CHEMISTRY,85(9),4729-4734. |
| MLA | Wei, Yanbo,et al."Polystyrene Spheres-Assisted Matrix-Assisted Laser Desorption Ionization Mass Spectrometry for Quantitative Analysis of Plasma Lysophosphatidylcholines".ANALYTICAL CHEMISTRY 85.9(2013):4729-4734. |
入库方式： OAI收割
来源：化学研究所
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