Shaped core/shell polymer nanoobjects with high antibacterial activities via block copolymer microphase separation
文献类型：期刊论文
| 作者 | Yao, Dongdong1; Guo, Yujuan2; Chen, Shiguo2; Tang, Jiaoning2; Chen, Yongming1 |
| 刊名 | POLYMER
 |
| 出版日期 | 2013-06-01 |
| 卷号 | 54期号:14页码:3485-3491 |
| 关键词 | Antibacterial Activities Block Copolymer Microphase Separation Shaped Polymer Nanoobjects |
| ISSN号 | 0032-3861 |
| DOI | 10.1016/j.polymer.2013.05.005 |
| 英文摘要 | We report a procedure to fabricate antibacterial core/shell polymer nanoobjects with sheetlike, cylindrical, and spherical shapes. These shaped nanoobjects with chemically cross-linked polysiloxane cores and densely grafted polyammoniums shells were prepared by dispersing cross-linked microphase-separated materials of diblock copolymers, poly(2-(dimethylamino)ethyl methacrylate)-block-poly (3-(triethoxysilyl)propyl methacrylate) (PDMAEMA-b-PTEPM). Shapes of the nanoobjects were controlled by block copolymer composition, namely the microphase-separated structures. Then the tethered PDMAEMA shells were further quaternized with n-octyl bromide. The diblock copolymers, microphase-separated materials and shaped nanoobjects before and after quaternization were studied by H-1 NMR, size exclusion chromatography (SEC), small-angle X-ray scattering (SAXS) and transmission electron microscopy (TEM), and Fourier-transform infrared spectroscopy (FT-IR). The antibacterial activities of these quaternized nanoobjects have been preliminarily assessed against bacteria Escherichia coli (E. coli) (8099). The minimum bactericidal concentration (MBC) of the sheets, cylinders and spheres were 1.00, 0.66, 0.66 mg/mL. The antibacterial activities of the quaternized nanoobjects were nearly ten times higher than that of quaternized PDMAEMA homopolymer. (C) 2013 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000320679600008 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/54119]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Chen, Shiguo |
| 作者单位 | 1.Chinese Acad Sci, Lab Polymer Phys & Chem, Inst Chem, Beijing 100190, Peoples R China 2.Shenzhen Univ, Shenzhen Key Lab Special Funct Mat, Coll Mat Sci & Engn, Shenzhen 518060, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yao, Dongdong,Guo, Yujuan,Chen, Shiguo,et al. Shaped core/shell polymer nanoobjects with high antibacterial activities via block copolymer microphase separation[J]. POLYMER,2013,54(14):3485-3491. |
| APA | Yao, Dongdong,Guo, Yujuan,Chen, Shiguo,Tang, Jiaoning,&Chen, Yongming.(2013).Shaped core/shell polymer nanoobjects with high antibacterial activities via block copolymer microphase separation.POLYMER,54(14),3485-3491. |
| MLA | Yao, Dongdong,et al."Shaped core/shell polymer nanoobjects with high antibacterial activities via block copolymer microphase separation".POLYMER 54.14(2013):3485-3491. |
入库方式： OAI收割
来源：化学研究所
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