Scab-Inspired Cytophilic Membrane of Anisotropic Nanofibers for Rapid Wound Healing
文献类型：期刊论文
| 作者 | Xi, Yanli1,2; Dong, Hua1; Sun, Kang1; Liu, Hongliang1; Liu, Ruiming1,3; Qin, Yuansen1,3; Hu, Zuojun1,3; Zhao, Yong1; Nie, Fuqiang1; Wang, Shutao1 |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2013-06-12 |
| 卷号 | 5期号:11页码:4821-4826 |
| 关键词 | Cytophilic Anisotropic Nanofibrous Membranes Wound Healing Cell Attachment Cell Migration |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/am4004683 |
| 英文摘要 | This work investigates the influence of cytophilic and anisotropic nanomaterials on accelerated cell attachment and directional migration toward rapid wound healing. Inspired by the anisotropic protein nanofibers in scab, a polyurethane (PU) nanofibrous membrane with an aligned structure was fabricated. The membrane showed good, affinity for wound-healing-related cells and could guide cell migration in the direction of PU nanofibers. Also, the morphology and distribution of P-actin and paxillin of attached cells were influenced by the underlying nanofibers. The randomly distributed PU nanofibers and planar PU membrane did not show a distinct impact on cell migration. This scab-inspired cytophilic membrane is promising in applications as functional interfacial biomaterials for rapid wound healing, bone repair, and construction of neural networks. |
| 语种 | 英语 |
| WOS记录号 | WOS:000320484000047 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/54259]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Shutao |
| 作者单位 | 1.Chinese Acad Sci, Beijing Natl Lab Mol Sci BNLMS, Key Lab Organ Solids, Inst Chem, Beijing 100190, Peoples R China 2.Jinlin Univ, Sch Publ Hlth, Changchun 130021, Peoples R China 3.Sun Yat Sen Univ, Dept Vasc Surg, Affiliated Hosp 1, Guangzhou 510080, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xi, Yanli,Dong, Hua,Sun, Kang,et al. Scab-Inspired Cytophilic Membrane of Anisotropic Nanofibers for Rapid Wound Healing[J]. ACS APPLIED MATERIALS & INTERFACES,2013,5(11):4821-4826. |
| APA | Xi, Yanli.,Dong, Hua.,Sun, Kang.,Liu, Hongliang.,Liu, Ruiming.,...&Wang, Shutao.(2013).Scab-Inspired Cytophilic Membrane of Anisotropic Nanofibers for Rapid Wound Healing.ACS APPLIED MATERIALS & INTERFACES,5(11),4821-4826. |
| MLA | Xi, Yanli,et al."Scab-Inspired Cytophilic Membrane of Anisotropic Nanofibers for Rapid Wound Healing".ACS APPLIED MATERIALS & INTERFACES 5.11(2013):4821-4826. |
入库方式： OAI收割
来源：化学研究所
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