Co-transplantation of neural stem cells and Schwann cells within poly (L-lactic-co-glycolic acid) scaffolds facilitates axonal regeneration in hemisected rat spinal cord
文献类型:期刊论文
作者 | Xia Lei1,2; Wan Hong1; Hao Shu-yu3; Li De-zhi3; Chen Gang4; Gao Chuan-chuan1,2; Li Jun-hua1; Yang Fei5; Wang Shen-guo5; Liu Song6,7 |
刊名 | CHINESE MEDICAL JOURNAL
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出版日期 | 2013-03-05 |
卷号 | 126期号:5页码:909-917 |
关键词 | Spinal Cord Injury Tissue Engineering Neural Stem Cells Schwann Cells Poly(L-lactic-co-glycolic Acid) Scaffold |
ISSN号 | 0366-6999 |
DOI | 10.3760/cma.j.issn.0366-6999.20120476 |
英文摘要 | Background Various tissue engineering strategies have been developed to facilitate axonal regeneration after spinal cord injury. This study aimed to investigate whether neural stem cells (NSCs) could survive in poly(L-lactic-co-glycolic acid) (PLGA) scaffolds and, when cografted with Schwann cells (SCs), could be induced to differentiate towards neurons which form synaptic connection and eventually facilitate axonal regeneration and myelination and motor function. |
语种 | 英语 |
WOS记录号 | WOS:000319783500022 |
出版者 | CHINESE MEDICAL ASSOC |
源URL | [http://ir.iccas.ac.cn/handle/121111/54313] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Wan Hong |
作者单位 | 1.Capital Med Univ, Beijing Neurosurg Inst, Beijing 100050, Peoples R China 2.Capital Med Univ, Beijing Sanbo Brain Hosp, Dept Neurosurg, Beijing 100093, Peoples R China 3.Capital Med Univ, Beijing Tiantan Hosp, Dept Neurosurg, Beijing 100050, Peoples R China 4.Wuxi 4 People Hosp, Dept Neurosurg, Wuxi 214062, Jiangsu, Peoples R China 5.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China 6.INSERM, F-94275 Le Kremlin Bicetre, France 7.Univ Paris 11, Le Kremlin Bicetre, France |
推荐引用方式 GB/T 7714 | Xia Lei,Wan Hong,Hao Shu-yu,et al. Co-transplantation of neural stem cells and Schwann cells within poly (L-lactic-co-glycolic acid) scaffolds facilitates axonal regeneration in hemisected rat spinal cord[J]. CHINESE MEDICAL JOURNAL,2013,126(5):909-917. |
APA | Xia Lei.,Wan Hong.,Hao Shu-yu.,Li De-zhi.,Chen Gang.,...&Liu Song.(2013).Co-transplantation of neural stem cells and Schwann cells within poly (L-lactic-co-glycolic acid) scaffolds facilitates axonal regeneration in hemisected rat spinal cord.CHINESE MEDICAL JOURNAL,126(5),909-917. |
MLA | Xia Lei,et al."Co-transplantation of neural stem cells and Schwann cells within poly (L-lactic-co-glycolic acid) scaffolds facilitates axonal regeneration in hemisected rat spinal cord".CHINESE MEDICAL JOURNAL 126.5(2013):909-917. |
入库方式: OAI收割
来源:化学研究所
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