Simple, Clean Preparation Method for Cross-Linked alpha-Cyclodextrin Nanoparticles via Inclusion Complexation
文献类型:期刊论文
作者 | Zhu, Wen; Zhang, Ke; Chen, Yongming; Xi, Fu |
刊名 | LANGMUIR
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出版日期 | 2013-05-21 |
卷号 | 29期号:20页码:5939-5943 |
ISSN号 | 0743-7463 |
DOI | 10.1021/la400478d |
英文摘要 | A simple, dean method was presented in this letter to prepare cross linked alpha-cyclodextrin (alpha-CD) nanoparticles with a low dispersion. The nanoparticles were synthesized in water by cross-linking the inclusion complex of alpha-CDs and poly(ethylene glycol) (PEG). The structure of the nanoparticles was characterized by H-1 NMR, nuclear overhauser enhancement spectroscopy (NOESY), and wide-angle X-ray diffraction (XRD). Spherical morphology was observed by scanning electron microscopy (SEM) for these nanoparticles. Their average hydrodynamic radius was determined to be 67 tun by dynamic light scattering (DLS). Small guest molecules could be included in the cross linked alpha-CD nanoparticles, and anticancer drug cisplatin was used to evaluate the drug release behavior. |
语种 | 英语 |
WOS记录号 | WOS:000319708400001 |
出版者 | AMER CHEMICAL SOC |
源URL | [http://ir.iccas.ac.cn/handle/121111/54681] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Chen, Yongming |
作者单位 | Chinese Acad Sci, Inst Chem, Lab Polymer Phys & Chem, Beijing 100190, Peoples R China |
推荐引用方式 GB/T 7714 | Zhu, Wen,Zhang, Ke,Chen, Yongming,et al. Simple, Clean Preparation Method for Cross-Linked alpha-Cyclodextrin Nanoparticles via Inclusion Complexation[J]. LANGMUIR,2013,29(20):5939-5943. |
APA | Zhu, Wen,Zhang, Ke,Chen, Yongming,&Xi, Fu.(2013).Simple, Clean Preparation Method for Cross-Linked alpha-Cyclodextrin Nanoparticles via Inclusion Complexation.LANGMUIR,29(20),5939-5943. |
MLA | Zhu, Wen,et al."Simple, Clean Preparation Method for Cross-Linked alpha-Cyclodextrin Nanoparticles via Inclusion Complexation".LANGMUIR 29.20(2013):5939-5943. |
入库方式: OAI收割
来源:化学研究所
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