Identification of Small Biomolecular Compounds by MALDI-TOF-Mass Spectrometry
文献类型：期刊论文
| 作者 | Huo, Qing1; Liu, Jianan2; Xiong, Shaoxiang2; Shi, Rongjian3 |
| 刊名 | ASIAN JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2013-12-01 |
| 卷号 | 25期号:18页码:10137-10143 |
| 关键词 | Matrix-assisted Laser Ionization Sensitivity Matrix Molecular Weight |
| ISSN号 | 0970-7077 |
| 英文摘要 | Matrix assisted laser desorption ionization time of flight mass spectrometry MALDI-TOF-MS was generally used to analyze macromolecular compounds. In this paper we study how to use the MALDI to determine the molecular weight of small molecule compounds, such as sugars, amino acids, clenbuterol, diphenylmethyl amines, plant hormones, etc. We also studied how to exploring the sensitivity of matrix and how to application the sensitivity. We find a macromolecular 1,2,3,4-tetrakis(3',4'-hydroxyphenyl)-thiophene as matrix, it not only absorbs the laser energy but also makes sample desorption ionization. At the same time it does not produce interfering ions to low molecular weight. In addition, perfluoro C-60 was added in matrix sensitivity can be improved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000332937600023 |
| 出版者 | ASIAN JOURNAL OF CHEMISTRY |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/54819]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Jianan |
| 作者单位 | 1.Beijing Union Univ, Biochem Engn Coll, Beijing 100023, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huo, Qing,Liu, Jianan,Xiong, Shaoxiang,et al. Identification of Small Biomolecular Compounds by MALDI-TOF-Mass Spectrometry[J]. ASIAN JOURNAL OF CHEMISTRY,2013,25(18):10137-10143. |
| APA | Huo, Qing,Liu, Jianan,Xiong, Shaoxiang,&Shi, Rongjian.(2013).Identification of Small Biomolecular Compounds by MALDI-TOF-Mass Spectrometry.ASIAN JOURNAL OF CHEMISTRY,25(18),10137-10143. |
| MLA | Huo, Qing,et al."Identification of Small Biomolecular Compounds by MALDI-TOF-Mass Spectrometry".ASIAN JOURNAL OF CHEMISTRY 25.18(2013):10137-10143. |
入库方式： OAI收割
来源：化学研究所
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