Quinoline-Based Fluorescent Probe for Ratiometric Detection of Lysosomal pH
文献类型:期刊论文
作者 | Li, Guoping1; Zhu, Dongjian1; Xue, Lin1; Jiang, Hua1,2 |
刊名 | ORGANIC LETTERS
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出版日期 | 2013-10-04 |
卷号 | 15期号:19页码:5020-5023 |
ISSN号 | 1523-7060 |
DOI | 10.1021/ol4023547 |
英文摘要 | A new pH-responsive fluorescent probe has been reported based on protonation-activable resonance charge transfer. In aqueous solution, probe PQ-Lyso exhibits ratiometric detection of pH changes with a large hypsochromic shift of 76 nm and remarkable changes in the fluorescence intensity ratio (R = F-494 (nm)/F-570 (nm), R/R-0 = 105). Furthermore, PQ-Lyso, which is localized to lysosomes in living cells, can calibrate lysosomal pH using fluorescence ratiometry. |
语种 | 英语 |
WOS记录号 | WOS:000326320200027 |
出版者 | AMER CHEMICAL SOC |
源URL | [http://ir.iccas.ac.cn/handle/121111/54893] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Xue, Lin |
作者单位 | 1.Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, CAS Key Lab Photochem, Beijing 100190, Peoples R China 2.Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Guoping,Zhu, Dongjian,Xue, Lin,et al. Quinoline-Based Fluorescent Probe for Ratiometric Detection of Lysosomal pH[J]. ORGANIC LETTERS,2013,15(19):5020-5023. |
APA | Li, Guoping,Zhu, Dongjian,Xue, Lin,&Jiang, Hua.(2013).Quinoline-Based Fluorescent Probe for Ratiometric Detection of Lysosomal pH.ORGANIC LETTERS,15(19),5020-5023. |
MLA | Li, Guoping,et al."Quinoline-Based Fluorescent Probe for Ratiometric Detection of Lysosomal pH".ORGANIC LETTERS 15.19(2013):5020-5023. |
入库方式: OAI收割
来源:化学研究所
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