Synthesis and gelation of N-stearoyl-L-glutamic acid and N-stearoyl-L-glutamic diethyl ester
文献类型：期刊论文
| 作者 | Gao, P; Liu, LZ; Zhan, CL; Zhou, YB; Liu, MH |
| 刊名 | ACTA CHIMICA SINICA
 |
| 出版日期 | 2004-05-14 |
| 卷号 | 62期号:9页码:895-900 |
| 关键词 | Organogel N-stearoyl-l-glutamic Acid Self-assembly Microstrutcure |
| ISSN号 | 0567-7351 |
| 英文摘要 | Synthesis of N-stearoyl-L-glutamic acid (C-18-Glu), a new gelator with multi-H-bonding sites, and N-stearoyl-L-glutamic diethyl ester (C-18-Glu-2ES) were reported. The previously reported synthetic route of C-18-Glu is that stearoyl chloride was dropwise added into disodium L-glutamate solution in a mixture of acetone and water (J. Am. Oil Chem. Soc. 1972, 49, 157 and Langmiur, 2001, 17, 1317). However, our experimental results indicated that one of the by-product HCl, could catalyze the yielded C-18-Glu to react further with L-glutamate to give more side-products. Therefore, the further workup became more difficult and the pure C-18-Glu was difficult to be obtained. Here, we synthesized C-18-Glu by the following two routes. One is from L-glutamic diethyl ester and steanic acid using dicyclohexylcarbodiimide (DCC) as a catalyzer. The other is from stearoyl chloride and L-glutamic diethyl ester. These two synthetic routes can all give out C-18-Ghr with satisfactory characteristic data. Moreover, The gelating properties of C-18-Ghr and C-18-Glu-2ES were also investigated. C-18-Glu can gel chloroform and 1 : 1 mixed ethanol/ water, while C-18-Glu-2ES can form organogels in more solvents such as petroleum ether, hexane, acetone, ethanol, and 3:7 mixed ethanol/water. AFM images indicated that C-18-Glu self-assembled into nanowires in chloroform, while C-18-Glu-2ES into lamellar-like microstructures in 3:7 mixed ethanol/water. |
| 语种 | 英语 |
| WOS记录号 | WOS:000221419800009 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/55059]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Gao, P |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Key Lab Colloid & Interface Sci, Beijing 100080, Peoples R China 2.Harbin Univ Sci & Technol, Coll Mat Sci & Engn, Harbin 150080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, P,Liu, LZ,Zhan, CL,et al. Synthesis and gelation of N-stearoyl-L-glutamic acid and N-stearoyl-L-glutamic diethyl ester[J]. ACTA CHIMICA SINICA,2004,62(9):895-900. |
| APA | Gao, P,Liu, LZ,Zhan, CL,Zhou, YB,&Liu, MH.(2004).Synthesis and gelation of N-stearoyl-L-glutamic acid and N-stearoyl-L-glutamic diethyl ester.ACTA CHIMICA SINICA,62(9),895-900. |
| MLA | Gao, P,et al."Synthesis and gelation of N-stearoyl-L-glutamic acid and N-stearoyl-L-glutamic diethyl ester".ACTA CHIMICA SINICA 62.9(2004):895-900. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。