The preparation of PLGA encapsulated Ca-alginate microspheres loaded with BSA and the release behavior of BSA
文献类型：期刊论文
| 作者 | Zhang, HW; Cai, Q; Bei, JZ; Wang, SG |
| 刊名 | ACTA POLYMERICA SINICA
 |
| 出版日期 | 2004-06-01 |
| 期号 | 3页码:454-457 |
| 关键词 | Ca-alginate Microspheres Bovine Serum Albumin (Bsa) Poly( l -lactic-co-glycolic Acid) (Plga) Release Behavior |
| ISSN号 | 1000-3304 |
| 英文摘要 | Alginate microspheres were formed by coagulation of sodium alginate in CaCl2 solutions, followed by lyophilization which could create the porous structure. Bovine serum albumin ( BSA ) was incorporated into the microspheres by mixing BSA with sodium alginate prior to coagulation. The release behavior of BSA from the Ca-alginate microspheres was studied. Further, the alginate microspheres loaded with BSA were embedded in PLGA films by mixing the alginate microspheres with PLGA solutions, in order to study the sustained release of BSA from the PLGA film, which is widely used as cell scaffold materials in tissue engineering. The release behavior of BSA from the PLGA film embedded alginate microspheres indicated potential application for keeping the bioactivity of the growth factor. |
| 语种 | 英语 |
| WOS记录号 | WOS:000222256700029 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/55099]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhang, HW |
| 作者单位 | Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, HW,Cai, Q,Bei, JZ,et al. The preparation of PLGA encapsulated Ca-alginate microspheres loaded with BSA and the release behavior of BSA[J]. ACTA POLYMERICA SINICA,2004(3):454-457. |
| APA | Zhang, HW,Cai, Q,Bei, JZ,&Wang, SG.(2004).The preparation of PLGA encapsulated Ca-alginate microspheres loaded with BSA and the release behavior of BSA.ACTA POLYMERICA SINICA(3),454-457. |
| MLA | Zhang, HW,et al."The preparation of PLGA encapsulated Ca-alginate microspheres loaded with BSA and the release behavior of BSA".ACTA POLYMERICA SINICA .3(2004):454-457. |
入库方式： OAI收割
来源：化学研究所
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