中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum

文献类型:期刊论文

作者Rao, J; Xie, J; Zhao, JQ; Zhu, T
刊名SCIENCE IN CHINA SERIES B-CHEMISTRY
出版日期2004-10-01
卷号47期号:5页码:381-387
关键词Chrysophanol Esr Semiquinone Radical Anions Superoxide Radical Anions Hydroxyl Radical Singlet Oxygen
ISSN号1006-9291
英文摘要In the current work, chryosphanol (MHAQ) was isolated and purified from rheum, and the photosensitization activities were studied. In nitrogen -saturated DMSO solution, irradiation of chryosphanol (MHAQ) with visible light (>430 nm) produced the serniquinone radical anions (MHAQ(.-)), which was intensified significantly by an electron donor NADH, suggesting electron transfer between the excited and ground state photosensitizer molecules. In an air-saturated DMSO solution, superoxide radical anions (O-2(.-)), trapped by DMPO, were detected. It was proved that O-2(.-) was not originated from the singlet oxygen (O-1(2)) but dependent on DMPO, chrysophanol, oxygen and the irradiation time. The singlet oxygen and (OH)-O-. could also be produced by the photosensitization of the pholosensitizer. These suggest that chrysophanol possesses the photosensitization activity via Type I mechanism and Type II mechanism. To evaluate the photosensitization activities of MHAQ, emodin and mixed anthraquinone derivatives extracted from rheum, the relative productivities Of O-2(.-) were estimated to be 1.8, 1.1 and 1.0 respectively and the quantum yields for singlet oxygen to be 0.36, 0.53 and 0.14 respectively. Therefore, these low-cost pigments may be potentially used as phototherapeutic medicine for some kind of vascular diseases or photo-activated pesticides.
语种英语
WOS记录号WOS:000225425000004
出版者SCIENCE CHINA PRESS
源URL[http://ir.iccas.ac.cn/handle/121111/55313]  
专题中国科学院化学研究所
通讯作者Zhao, JQ
作者单位1.Chinese Acad Sci, Key Lab Photochem, Ctr Mol Sci, Inst Chem, Beijing 100080, Peoples R China
2.Univ Sci & Technol Beijing, Beijing 10083, Peoples R China
推荐引用方式
GB/T 7714
Rao, J,Xie, J,Zhao, JQ,et al. Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2004,47(5):381-387.
APA Rao, J,Xie, J,Zhao, JQ,&Zhu, T.(2004).Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum.SCIENCE IN CHINA SERIES B-CHEMISTRY,47(5),381-387.
MLA Rao, J,et al."Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum".SCIENCE IN CHINA SERIES B-CHEMISTRY 47.5(2004):381-387.

入库方式: OAI收割

来源:化学研究所

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