Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum
文献类型：期刊论文
| 作者 | Rao, J; Xie, J; Zhao, JQ; Zhu, T |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2004-10-01 |
| 卷号 | 47期号:5页码:381-387 |
| 关键词 | Chrysophanol Esr Semiquinone Radical Anions Superoxide Radical Anions Hydroxyl Radical Singlet Oxygen |
| ISSN号 | 1006-9291 |
| 英文摘要 | In the current work, chryosphanol (MHAQ) was isolated and purified from rheum, and the photosensitization activities were studied. In nitrogen -saturated DMSO solution, irradiation of chryosphanol (MHAQ) with visible light (>430 nm) produced the serniquinone radical anions (MHAQ(.-)), which was intensified significantly by an electron donor NADH, suggesting electron transfer between the excited and ground state photosensitizer molecules. In an air-saturated DMSO solution, superoxide radical anions (O-2(.-)), trapped by DMPO, were detected. It was proved that O-2(.-) was not originated from the singlet oxygen (O-1(2)) but dependent on DMPO, chrysophanol, oxygen and the irradiation time. The singlet oxygen and (OH)-O-. could also be produced by the photosensitization of the pholosensitizer. These suggest that chrysophanol possesses the photosensitization activity via Type I mechanism and Type II mechanism. To evaluate the photosensitization activities of MHAQ, emodin and mixed anthraquinone derivatives extracted from rheum, the relative productivities Of O-2(.-) were estimated to be 1.8, 1.1 and 1.0 respectively and the quantum yields for singlet oxygen to be 0.36, 0.53 and 0.14 respectively. Therefore, these low-cost pigments may be potentially used as phototherapeutic medicine for some kind of vascular diseases or photo-activated pesticides. |
| 语种 | 英语 |
| WOS记录号 | WOS:000225425000004 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/55313]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, JQ |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Photochem, Ctr Mol Sci, Inst Chem, Beijing 100080, Peoples R China 2.Univ Sci & Technol Beijing, Beijing 10083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Rao, J,Xie, J,Zhao, JQ,et al. Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2004,47(5):381-387. |
| APA | Rao, J,Xie, J,Zhao, JQ,&Zhu, T.(2004).Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum.SCIENCE IN CHINA SERIES B-CHEMISTRY,47(5),381-387. |
| MLA | Rao, J,et al."Photogeneration of the free radicals and singlet oxygen by chrysophanol from rheum".SCIENCE IN CHINA SERIES B-CHEMISTRY 47.5(2004):381-387. |
入库方式： OAI收割
来源：化学研究所
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