Synthesis of biodegradable polylactone-grafted polyphosphazene copolymers
文献类型：期刊论文
| 作者 | Cai, Q; Zhang, T; Bei, JZ; Wang, SG; Jin, RG |
| 刊名 | ACTA POLYMERICA SINICA
 |
| 出版日期 | 2005-04-01 |
| 期号 | 2页码:236-239 |
| 关键词 | Polyphosphazene Polyester Graft Biodegradable |
| ISSN号 | 1000-3304 |
| 英文摘要 | A primary study on the synthesis of polylactone- grafted polyphosphazene copolymers has been carried out for the purpose of using them as cell scaffold material in tissue engineering. It was found that the copolymer could be obtained via transesterification of hydroxyl-ended polylactone, such as polycaprolactone (PCL) and polylactide (PLA), with poly [bis( glycine ethyl ester) phosphazene ] (PGP). However, it was needed to note that this process seemed more suitable for the preparation of PCL-grafted polyphosphazene copolymer than for other polylactone-grafted polyphosphazene copolymers, because the melting point of PCL (ca. 60 degrees C) was far below the reaction temperature (160 degrees C) which facilitated the mixing of the two polymers. Moreover, the transesterification of PCL with PGP could proceed satisfactorily only if the molecular weight of PCL was less than 8000,which was considered due to the weakened reactivity of hydroxyl end groups with molecular weight increase. Further detailed study is underway to optimize the reaction and it will be focused on the thermostability of poly[(amino acid alkyl ester) phosphazenes] influencing the transesterification. |
| 语种 | 英语 |
| WOS记录号 | WOS:000228686200016 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/56165]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Cai, Q |
| 作者单位 | 1.Beijing Univ Chem Technol, Coll Mat Sci & Engn, Beijing 100029, Peoples R China 2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cai, Q,Zhang, T,Bei, JZ,et al. Synthesis of biodegradable polylactone-grafted polyphosphazene copolymers[J]. ACTA POLYMERICA SINICA,2005(2):236-239. |
| APA | Cai, Q,Zhang, T,Bei, JZ,Wang, SG,&Jin, RG.(2005).Synthesis of biodegradable polylactone-grafted polyphosphazene copolymers.ACTA POLYMERICA SINICA(2),236-239. |
| MLA | Cai, Q,et al."Synthesis of biodegradable polylactone-grafted polyphosphazene copolymers".ACTA POLYMERICA SINICA .2(2005):236-239. |
入库方式： OAI收割
来源：化学研究所
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