Distinguishing malignant from normal stomach tissues and its in vivo, in situ measurement in operating process using FTIR Fiber-Optic techniques
文献类型：期刊论文
| 作者 | Xu, YZ; Yang, LM; Xu, Z; Zhao, Y; Ling, XF; Li, OB; Wang, JS; Zhang, NW; Zhang, YF; Wu, JG |
| 刊名 | SCIENCE IN CHINA SERIES B-CHEMISTRY
 |
| 出版日期 | 2005-04-01 |
| 卷号 | 48期号:2页码:167-175 |
| 关键词 | Ftir Fiber-optics Stomach Tissues Cancer Diagnosis |
| ISSN号 | 1006-9291 |
| DOI | 10.1360/04yb0135 |
| 英文摘要 | Gastric tissue samples were studied using mid-IR fiber-optic attenuated total reflectance (ATR) spectroscopy. FTIR spectra of 90 tissue samples from 48 patients, including 32 normal and 58 malignant tissue samples, were chosen as examples. Malignancy was usually characterized by the absence of CH and C=O bands, a weak amide II band near 1545 cm(-1), a shift of the amide I band to lower wave number, a decrease in the similar to 1450 cm(-1) peak to less than the similar to 1400 cm(-1) peak. Subtraction spectra indicate that the amide I and amide II bands of normal and malignant tissues have larger differences in peak positions and relative intensities. The statistical analysis results confirm this conclusion. The results indicate that FTIR fiber optic techniques provide important information about cancerous tissue of the stomach, which can be used to differentiate the malignant tissue from the normal tissue. Based on the above results we successfully realize the detection of the tumor tissues of digestive tract in vivo and in situ. And the results of detection cancer near operating room and in vivo and in situ in the operating room are consistent with the conclusions for the samples stored in liquid N-2, which is the basis for the clinical application. |
| 语种 | 英语 |
| WOS记录号 | WOS:000229230700011 |
| 出版者 | SCIENCE CHINA PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/56411]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wu, JG |
| 作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, State Key lab Rare Earth Mat & Applicat, Beijing 100871, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China 3.Peking Univ, Hosp 3, Dept Surg, Beijing 100083, Peoples R China 4.Xian Jiaotong Univ, Hosp 1, Dept Oncol, Xian 710061, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, YZ,Yang, LM,Xu, Z,et al. Distinguishing malignant from normal stomach tissues and its in vivo, in situ measurement in operating process using FTIR Fiber-Optic techniques[J]. SCIENCE IN CHINA SERIES B-CHEMISTRY,2005,48(2):167-175. |
| APA | Xu, YZ.,Yang, LM.,Xu, Z.,Zhao, Y.,Ling, XF.,...&Wu, JG.(2005).Distinguishing malignant from normal stomach tissues and its in vivo, in situ measurement in operating process using FTIR Fiber-Optic techniques.SCIENCE IN CHINA SERIES B-CHEMISTRY,48(2),167-175. |
| MLA | Xu, YZ,et al."Distinguishing malignant from normal stomach tissues and its in vivo, in situ measurement in operating process using FTIR Fiber-Optic techniques".SCIENCE IN CHINA SERIES B-CHEMISTRY 48.2(2005):167-175. |
入库方式： OAI收割
来源：化学研究所
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