The photo sensitization activity of a water-soluble carboxylate of hypocrellin B
文献类型:期刊论文
作者 | Zhao, YW; Xie, H; Zhao, JQ |
刊名 | DYES AND PIGMENTS
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出版日期 | 2005-07-01 |
卷号 | 66期号:1页码:61-68 |
关键词 | Hypocrellin Photosensitization Activity Molecular Polarity Phototherapeutic Window Electronic Paramagnetic Resonance Amphiphilicity |
ISSN号 | 0143-7208 |
DOI | 10.1016/j.dyepig.2004.08.015 |
英文摘要 | Based on theoretical prediction of the molecular polarity, water-soluble sodium HB-14-carboxylate (SCHB) was prepared and its photosensitization activity was evaluated. SCHB shows not only very good amphiphilicity but also much stronger absorption at 620 nm than its parents. In DMSO-PBS (3:1 by volume) solution (pH 7.4) of SCHB, the photosensitization generated the serniquinone anion radicals (SCHB.-) under anaerobic condition or superoxide anion radicals (O-2(.-)) in the presence of oxygen. In the oxygenated PBS solution of SCHB, hydroxyl radicals ((OH)-O-.) were photogenerated. In addition, SCHB could also be photosensitized to generate singlet oxygen (O-1(2)) with a quantum yield about 0.26. These findings suggest that SCHB can exert photodynamic action via photosensitization. (C) 2004 Elsevier Ltd. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000227198700010 |
出版者 | ELSEVIER SCI LTD |
源URL | [http://ir.iccas.ac.cn/handle/121111/56497] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Zhao, JQ |
作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Key Lab Photochem, Beijing 100080, Peoples R China |
推荐引用方式 GB/T 7714 | Zhao, YW,Xie, H,Zhao, JQ. The photo sensitization activity of a water-soluble carboxylate of hypocrellin B[J]. DYES AND PIGMENTS,2005,66(1):61-68. |
APA | Zhao, YW,Xie, H,&Zhao, JQ.(2005).The photo sensitization activity of a water-soluble carboxylate of hypocrellin B.DYES AND PIGMENTS,66(1),61-68. |
MLA | Zhao, YW,et al."The photo sensitization activity of a water-soluble carboxylate of hypocrellin B".DYES AND PIGMENTS 66.1(2005):61-68. |
入库方式: OAI收割
来源:化学研究所
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