中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy

文献类型:期刊论文

作者Lin, Y; Wang, J; Wan, LJ; Fang, XH
刊名ULTRAMICROSCOPY
出版日期2005-11-01
卷号105期号:1-4页码:129-136
关键词Atomic Force Microscopy (Afm) Fibrinogen Self-assembled Monolayer (Sam) Haemocompatibility
ISSN号0304-3991
DOI10.1016/j.ultramic.2005.06.028
英文摘要The adsorption of plasma protein fibrinogen on the self-assembled monolayers (SAMs) of n-hexadecyl mercaptan and citrate was investigated with atomic force microscopy (AFM). On the basis of the preparation of these two flat SAMs on Au(111), high-resolution AFM images of bovine fibrinogen were obtained with different protein concentrations. The results indicated that the surface chemical composition significantly affected the adsorption behavior of fibrinogen. Since fibrinogen plays a key role in the regulation of both haemostasis and thrombosis, high-resolution AFM imaging on SAMs is expected to be an effective approach to study the haernocompatibility of materials with different surface chemistry. (c) 2005 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000233317300021
出版者ELSEVIER SCIENCE BV
源URL[http://ir.iccas.ac.cn/handle/121111/56557]  
专题中国科学院化学研究所
通讯作者Fang, XH
作者单位1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Lin, Y,Wang, J,Wan, LJ,et al. Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy[J]. ULTRAMICROSCOPY,2005,105(1-4):129-136.
APA Lin, Y,Wang, J,Wan, LJ,&Fang, XH.(2005).Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy.ULTRAMICROSCOPY,105(1-4),129-136.
MLA Lin, Y,et al."Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy".ULTRAMICROSCOPY 105.1-4(2005):129-136.

入库方式: OAI收割

来源:化学研究所

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