Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy
文献类型:期刊论文
作者 | Lin, Y; Wang, J; Wan, LJ; Fang, XH |
刊名 | ULTRAMICROSCOPY
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出版日期 | 2005-11-01 |
卷号 | 105期号:1-4页码:129-136 |
关键词 | Atomic Force Microscopy (Afm) Fibrinogen Self-assembled Monolayer (Sam) Haemocompatibility |
ISSN号 | 0304-3991 |
DOI | 10.1016/j.ultramic.2005.06.028 |
英文摘要 | The adsorption of plasma protein fibrinogen on the self-assembled monolayers (SAMs) of n-hexadecyl mercaptan and citrate was investigated with atomic force microscopy (AFM). On the basis of the preparation of these two flat SAMs on Au(111), high-resolution AFM images of bovine fibrinogen were obtained with different protein concentrations. The results indicated that the surface chemical composition significantly affected the adsorption behavior of fibrinogen. Since fibrinogen plays a key role in the regulation of both haemostasis and thrombosis, high-resolution AFM imaging on SAMs is expected to be an effective approach to study the haernocompatibility of materials with different surface chemistry. (c) 2005 Elsevier B.V. All rights reserved. |
语种 | 英语 |
WOS记录号 | WOS:000233317300021 |
出版者 | ELSEVIER SCIENCE BV |
源URL | [http://ir.iccas.ac.cn/handle/121111/56557] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Fang, XH |
作者单位 | 1.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
推荐引用方式 GB/T 7714 | Lin, Y,Wang, J,Wan, LJ,et al. Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy[J]. ULTRAMICROSCOPY,2005,105(1-4):129-136. |
APA | Lin, Y,Wang, J,Wan, LJ,&Fang, XH.(2005).Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy.ULTRAMICROSCOPY,105(1-4),129-136. |
MLA | Lin, Y,et al."Study of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy".ULTRAMICROSCOPY 105.1-4(2005):129-136. |
入库方式: OAI收割
来源:化学研究所
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