Monitoring of the conversion from triptolide to tripchlorolide in triptergium wilfordii by micellar electrokinetic caillary chromatography
文献类型：期刊论文
| 作者 | Li, BZ; Bai, J; Yang, GL; Li, ZW; Wang, LJ; Chen, Y |
| 刊名 | JOURNAL OF CHROMATOGRAPHY A
 |
| 出版日期 | 2005-12-02 |
| 卷号 | 1097期号:1-2页码:199-202 |
| 关键词 | Micellar Electrokinetic Capillary Chromatography Triptolide Tripchlorolide Tripterygium Wilfordii Hook f |
| ISSN号 | 0021-9673 |
| DOI | 10.1016/j.chroma.2005.06.043 |
| 英文摘要 | A novel concocting method to convert Triptolide (T) into Tripchlorolide (T-4) in the traditional Chinese herb Tripterygium wilfordii Hook F. and a micellar electrokinetic capillary chromatographic (MEKC) approach by which the conversion of Triptolide (T) and Tripchlorolide (T-4) was identified and determined had been established. Investigations of the influence of different pH values of boric acid and borax buffer and of sodium dodecyl sulfate (SDS) and organic additive concentrations had been carried out, and the optimum separation for T and T-4 was achieved using boric acid and borax of pH 7.0 with 30 mM SDS and 20% (volume ratio) methanol as the running buffer. It was found that MEKC exhibited good accuracy, precision and repeatability and the content of T4 was greatly increased in the herb that was treated by the new concocting method. (c) 2005 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000233672400025 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/57249]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Yang, GL |
| 作者单位 | 1.Hebei Univ, Coll Pharm, Baoding 071002, Peoples R China 2.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China 3.Handan Univ, Dept Chem, Handan 056005, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, BZ,Bai, J,Yang, GL,et al. Monitoring of the conversion from triptolide to tripchlorolide in triptergium wilfordii by micellar electrokinetic caillary chromatography[J]. JOURNAL OF CHROMATOGRAPHY A,2005,1097(1-2):199-202. |
| APA | Li, BZ,Bai, J,Yang, GL,Li, ZW,Wang, LJ,&Chen, Y.(2005).Monitoring of the conversion from triptolide to tripchlorolide in triptergium wilfordii by micellar electrokinetic caillary chromatography.JOURNAL OF CHROMATOGRAPHY A,1097(1-2),199-202. |
| MLA | Li, BZ,et al."Monitoring of the conversion from triptolide to tripchlorolide in triptergium wilfordii by micellar electrokinetic caillary chromatography".JOURNAL OF CHROMATOGRAPHY A 1097.1-2(2005):199-202. |
入库方式： OAI收割
来源：化学研究所
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