Facile synthesis and optical resolution of inherently chiral fluorescent calix[4]crowns: enantioselective recognition towards chiral leucinol
文献类型：期刊论文
| 作者 | Luo, J; Zheng, QY; Chen, CF; Huang, ZT |
| 刊名 | TETRAHEDRON
 |
| 出版日期 | 2005-08-29 |
| 卷号 | 61期号:35页码:8517-8528 |
| 关键词 | Calix[4]Crown Inherently Chiral Synthesis Optical Resolution Enantioselective Recognition |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet.2005.06.015 |
| 英文摘要 | A series of tri-O-alkylated inherently chiral fluorescent calix[4]crowns in the cone conformations and a series of tetra-O-alkylated inherently chiral fluorescent calix[4]crowns in the partial cone conformations have been synthesized. By condensing with chiral auxiliary (S)-BINOL, the resulting diastereomers could be separated via preparative TLC. We found that the size of the crown moiety effected the separation of the diastereomers. Further, removal of the BINOL unit by hydrolysis furnished pairs of enantiomers with optical purity. Moreover, we found that a tetra-O-alkylated inherently chiral fluorescent calix[4]crown-6 in the partial cone conformation 6c showed considerable enantioselective recognition capability towards chiral leucinol. (c) 2005 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000231211800026 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/57369]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Chen, CF |
| 作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Biol Chem Lab, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Luo, J,Zheng, QY,Chen, CF,et al. Facile synthesis and optical resolution of inherently chiral fluorescent calix[4]crowns: enantioselective recognition towards chiral leucinol[J]. TETRAHEDRON,2005,61(35):8517-8528. |
| APA | Luo, J,Zheng, QY,Chen, CF,&Huang, ZT.(2005).Facile synthesis and optical resolution of inherently chiral fluorescent calix[4]crowns: enantioselective recognition towards chiral leucinol.TETRAHEDRON,61(35),8517-8528. |
| MLA | Luo, J,et al."Facile synthesis and optical resolution of inherently chiral fluorescent calix[4]crowns: enantioselective recognition towards chiral leucinol".TETRAHEDRON 61.35(2005):8517-8528. |
入库方式： OAI收割
来源：化学研究所
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