Synthesis and optical resolution of a series of inherently chiral calix[4]crowns with cone and partial cone conformations
文献类型：期刊论文
| 作者 | Luo, J; Zheng, QY; Chen, CF; Huang, ZT |
| 刊名 | CHEMISTRY-A EUROPEAN JOURNAL
 |
| 出版日期 | 2005-10-07 |
| 卷号 | 11期号:20页码:5917-5928 |
| 关键词 | Calixarenes Chirality Crown Compounds Optical Resolution Synthesis |
| ISSN号 | 0947-6539 |
| DOI | 10.1002/chem.200500272 |
| 英文摘要 | A series of inherently chiral calix[4]arenes with cone and partial cone conformations and with crown ether moieties of variable size have been readily synthesized. By taking advantage of the carboxy appendage on the lower rim, these were condensed with the chiral auxiliary (S)-BINOL to form diastereomers which, in most cases, could be separated by preparative TLC, or more desirably, by column chromatography on silica gel (diastereomeric excess > 99% based on HPLC analysis). Seven enantiopure antipodes of inherently chiral calix[4]crowns were obtained after hydrolysis. It has been found that both the size of the crown moiety and alkylation of the last phenolic hydroxy group (accompanied with or without a change in the conformation) affect the separation of the diastereomers. |
| 语种 | 英语 |
| WOS记录号 | WOS:000232567700013 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/57515]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Chen, CF |
| 作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Luo, J,Zheng, QY,Chen, CF,et al. Synthesis and optical resolution of a series of inherently chiral calix[4]crowns with cone and partial cone conformations[J]. CHEMISTRY-A EUROPEAN JOURNAL,2005,11(20):5917-5928. |
| APA | Luo, J,Zheng, QY,Chen, CF,&Huang, ZT.(2005).Synthesis and optical resolution of a series of inherently chiral calix[4]crowns with cone and partial cone conformations.CHEMISTRY-A EUROPEAN JOURNAL,11(20),5917-5928. |
| MLA | Luo, J,et al."Synthesis and optical resolution of a series of inherently chiral calix[4]crowns with cone and partial cone conformations".CHEMISTRY-A EUROPEAN JOURNAL 11.20(2005):5917-5928. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。