Bulk and surface modifications of polylactide
文献类型：期刊论文
| 作者 | Wang, SG; Cui, WJ; Bei, JZ |
| 刊名 | ANALYTICAL AND BIOANALYTICAL CHEMISTRY
 |
| 出版日期 | 2005-02-01 |
| 卷号 | 381期号:3页码:547-556 |
| 关键词 | Polylactide Bulk Modification Surface Modification Hydrophilicity Cell Affinity Tissue Engineering |
| ISSN号 | 1618-2642 |
| DOI | 10.1002/s00216-004-27712 |
| 英文摘要 | This article reviews various methods of modifying the bulk and surface properties of poly(lactic acid) (PLA) so that the polymer may be used as a drug carrier in a drug delivery system (DDS) and as a cell scaffold in tissue engineering. Copolymerization of lactide with other lactone-type monomers or monomers with functional groups such as malic acid, copolymerization of lactide with macromolecular monomer such as poly(ethylene glycol) (PEG) or dextran, as well as blending polylactide and natural derivatives and other methods of bulk modification are discussed. Surface modifications of PLA-type copolymers, such as surface coating, chemical modification, and plasma treatment are described. Cell culture technology proves the efficiency of bulk and surface modification and the potential application of PLA in tissue engineering. |
| 语种 | 英语 |
| WOS记录号 | WOS:000227697400005 |
| 出版者 | SPRINGER HEIDELBERG |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/57701]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, SG |
| 作者单位 | Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, SG,Cui, WJ,Bei, JZ. Bulk and surface modifications of polylactide[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2005,381(3):547-556. |
| APA | Wang, SG,Cui, WJ,&Bei, JZ.(2005).Bulk and surface modifications of polylactide.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,381(3),547-556. |
| MLA | Wang, SG,et al."Bulk and surface modifications of polylactide".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 381.3(2005):547-556. |
入库方式： OAI收割
来源：化学研究所
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