中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A carbon fiber microelectrode-based third-generation biosensor for superoxide anion

文献类型:期刊论文

作者Tian, Y; Mao, LQ; Okajima, T; Ohsaka, T
刊名BIOSENSORS & BIOELECTRONICS
出版日期2005-10-15
卷号21期号:4页码:557-564
关键词Superoxide Anion (O-2(Center Dot-)) Biosensor Carbon Fiber Microelectrode (Cfme) Superoxide Dismutase (Sod) Cysteine
ISSN号0956-5663
DOI10.1016/j.bios.2004.12.006
英文摘要Implantable and miniature carbon fiber microelectrode (CFME)-based third-generation biosensor for superoxide anion (O-2(center dot-)) was fabricated for the first time. The CFME-based biosensor was constructed by electro-deposition of An nanoparticles on the CFMEs and then modification of the Au nanoparticles by cysteine followed by immobilization of superoxide dismutase (SOD) on the electrodes. The direct electrochemistry of the SOD immobilized on the CFME-based electrodes was efficiently realized by electron transfer promoter - cysteine molecules confined on the An nanoparticles deposited on the CFMEs. The CFME-based biosensors were demonstrated to possess striking analytical properties for O-2(center dot-) determination, such as optional operation potentials, high selectivity and sensitivity as well as good stability. Along with the implantable capacity inherent in the CFMEs, these striking analytical properties of the CFME-based biosensors substantially make them potential for in vivo determination of O-2(center dot-). (c) 2004 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000232818500003
出版者ELSEVIER ADVANCED TECHNOLOGY
源URL[http://ir.iccas.ac.cn/handle/121111/57725]  
专题中国科学院化学研究所
通讯作者Ohsaka, T
作者单位1.Tokyo Inst Technol, Dept Elect Chem, Interdisciplinary Grad Sch Sci & Engn, Midori Ku, Yokohama, Kanagawa 2268502, Japan
2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
推荐引用方式
GB/T 7714
Tian, Y,Mao, LQ,Okajima, T,et al. A carbon fiber microelectrode-based third-generation biosensor for superoxide anion[J]. BIOSENSORS & BIOELECTRONICS,2005,21(4):557-564.
APA Tian, Y,Mao, LQ,Okajima, T,&Ohsaka, T.(2005).A carbon fiber microelectrode-based third-generation biosensor for superoxide anion.BIOSENSORS & BIOELECTRONICS,21(4),557-564.
MLA Tian, Y,et al."A carbon fiber microelectrode-based third-generation biosensor for superoxide anion".BIOSENSORS & BIOELECTRONICS 21.4(2005):557-564.

入库方式: OAI收割

来源:化学研究所

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