中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers

文献类型:期刊论文

作者Yu, Haijun; Wang, Wenshou; Chen, Xuesi; Deng, Chao; Jing, Xiabin
刊名BIOPOLYMERS
出版日期2006-10-15
卷号83期号:3页码:233-242
关键词Amphiphilic Chitosan Graft Copolymer Nanoparticles Pcl
ISSN号0006-3525
DOI10.1002/bip.20551
英文摘要A novel synthetic approach to biodegradable amphiphilic copolymers based on poly (epsilon-caprolactone) (PCL) and chitosan was presented, and the prepared copolymers were used to prepare nanoparticles successfully. The PCL-graft-chitosan copolymers were synthesized by coupling the hydroxyl end-groups on preformed PCL chains and the amino groups present on 6-O-triphenylmethyl chitosan and by removing the protective 6-O-triphenylmethyl groups in acidic aqueous solution. The PCL content in the copolymers can be controlled in the range of 10-90 wt %. The graft copolymers were thoroughly characterized by H-1 NAM, C-13 NMR, FT-IR and DSC. The nanoparticles made from the graft copolymers were investigated by H-1 NMR, DLS, AFM and SEM measurements. It was found that the copolymers could form spherical or elliptic nanoparticles it? water. The amount of available primary amines on the surface of the prepared nanoparticles was evaluated by ninhydrin assail, and it can be controlled by the grafting degree of PCL. (c) 2006 Wiley Periodicals, Inc.
语种英语
WOS记录号WOS:000240709800004
出版者JOHN WILEY & SONS INC
源URL[http://ir.iccas.ac.cn/handle/121111/58081]  
专题中国科学院化学研究所
通讯作者Jing, Xiabin
作者单位1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式
GB/T 7714
Yu, Haijun,Wang, Wenshou,Chen, Xuesi,et al. Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers[J]. BIOPOLYMERS,2006,83(3):233-242.
APA Yu, Haijun,Wang, Wenshou,Chen, Xuesi,Deng, Chao,&Jing, Xiabin.(2006).Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers.BIOPOLYMERS,83(3),233-242.
MLA Yu, Haijun,et al."Synthesis and characterization of the biodegradable polycaprolactone-graft-chitosan amphiphilic copolymers".BIOPOLYMERS 83.3(2006):233-242.

入库方式: OAI收割

来源:化学研究所

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