Spectroscopic studies of the interaction between methylene blue and G-quadruplex
文献类型：期刊论文
| 作者 | Sun, Hongxia; Xiang, Junfeng; Zhang, Yazhou; Xu, Guangzhi; Xu, Lianghua; Tang, Yalin |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2006-07-01 |
| 卷号 | 51期号:14页码:1687-1692 |
| 关键词 | G-quadruplex Methyl Blue Absorption Fluorescence |
| ISSN号 | 1001-6538 |
| DOI | 10.1007/s11434-006-2025-0 |
| 英文摘要 | G-rich single-stranded DNA (5'-TTAGGG-3') adopted a G-quadruplex structure in buffer containing potassium ions. The spectroscopic feature and the interaction between methylene blue and G-quadruplex have been investigated by circular dichroism, and nuclear magnetic resonance spectroscopy. The UV-Vis absorption and fluorescence spectral results show that the fluorescence behavior of MB by single-stranded DNA fits Stern-Volmer static quenching equation very well and they formed 1 : 1 complexes; dimeric G-quadruplexes were bound to MB with 1 : 1 or 2 : 1, and their equilibrium constants were 1.047x10(5) and 8.79x10(4) L/mol, respectively. Based on the above results and (1)H-NMR spectral data, one may conclude that MB stacked either the terminal tetrads to form 1 : 1 complexes or between two terminal tetrads of G-quadruplexes to form 1 : 2 sandwich complexes with G-qudruplexes. |
| 语种 | 英语 |
| WOS记录号 | WOS:000240391900006 |
| 出版者 | SCIENCE PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/58155]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xu, Lianghua |
| 作者单位 | 1.Beijing Univ Chem Technol, Coll Mat Sci & Engn, Beijing 100029, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Hongxia,Xiang, Junfeng,Zhang, Yazhou,et al. Spectroscopic studies of the interaction between methylene blue and G-quadruplex[J]. CHINESE SCIENCE BULLETIN,2006,51(14):1687-1692. |
| APA | Sun, Hongxia,Xiang, Junfeng,Zhang, Yazhou,Xu, Guangzhi,Xu, Lianghua,&Tang, Yalin.(2006).Spectroscopic studies of the interaction between methylene blue and G-quadruplex.CHINESE SCIENCE BULLETIN,51(14),1687-1692. |
| MLA | Sun, Hongxia,et al."Spectroscopic studies of the interaction between methylene blue and G-quadruplex".CHINESE SCIENCE BULLETIN 51.14(2006):1687-1692. |
入库方式： OAI收割
来源：化学研究所
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