Influences of ammonia plasma treatment on modifying depth and degradation of poly(L-lactide) scaffolds
文献类型：期刊论文
| 作者 | Wan, YQ; Tu, CF; Yang, JA; Bei, JZ; Wang, SG |
| 刊名 | BIOMATERIALS
 |
| 出版日期 | 2006-05-01 |
| 卷号 | 27期号:13页码:2699-2704 |
| 关键词 | Poly(L-lactide) Plasma Surface Modification Degradation Cell Scaffold Cell Affinity |
| ISSN号 | 0142-9612 |
| DOI | 10.1016/j.biomaterials.2005.12.007 |
| 英文摘要 | Hydrophobicity of poly(L-lactide) scaffolds is a main drawback in obtaining a sufficient mass of seeded cells for satisfying the requirements of tissue engineering. Plasma treatment is a useful technique to enhance the hydrophilicity of the scaffolds. However, the effect of this technique on the modifying depth and degradation of the scaffolds should be considered. In this paper, the influence of NH3 plasma treatment on the modifying depth and degradation of scaffolds were investigated. The results showed that the modifying depth of the scaffolds increased with treating time and the plasma power ranging from 20 to 80 W influenced the depth slightly. However, the degradation of the scaffolds increased with increasing treatment time and plasma power. The results also showed that the plasma intruded the scaffolds gradually from top to bottom. For a 4 mm thick scaffold, the optimized treatment condition was 20 W of power in a 30 Pa ammonia atmosphere for 30 min of treating time. Under this condition, the integrity of scaffold could be relatively well kept. NH3 plasma treatment enabled the penetration of cells into scaffolds and facilitated the proliferation of cells in them. (c) 2005 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000235862600005 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/58219]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, SG |
| 作者单位 | Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wan, YQ,Tu, CF,Yang, JA,et al. Influences of ammonia plasma treatment on modifying depth and degradation of poly(L-lactide) scaffolds[J]. BIOMATERIALS,2006,27(13):2699-2704. |
| APA | Wan, YQ,Tu, CF,Yang, JA,Bei, JZ,&Wang, SG.(2006).Influences of ammonia plasma treatment on modifying depth and degradation of poly(L-lactide) scaffolds.BIOMATERIALS,27(13),2699-2704. |
| MLA | Wan, YQ,et al."Influences of ammonia plasma treatment on modifying depth and degradation of poly(L-lactide) scaffolds".BIOMATERIALS 27.13(2006):2699-2704. |
入库方式： OAI收割
来源：化学研究所
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