Immobilization of Rhodococcus sp AJ270 in alginate capsules and its application in enantio selective biotransformation of trans-2-methyl-3-phenyl-oxiranecarbonitrile and amide
文献类型：期刊论文
| 作者 | Guo, XL; Deng, G; Xu, J; Wang, MX |
| 刊名 | ENZYME AND MICROBIAL TECHNOLOGY
 |
| 出版日期 | 2006-06-01 |
| 卷号 | 39期号:1页码:1-5 |
| 关键词 | Encapsulation Rhodococcus Sp Aj270 Enantioselective Biotransformation Nitrile Hydratase Amidase |
| ISSN号 | 0141-0229 |
| DOI | 10.1016/j.enzmictec.2005.01.044 |
| 英文摘要 | Rhodococcus sp. AJ270, a nitrile hydratase/amidase-containing microorganism, were immobilized in alginate capsules. The influences of the bead size and the crosslinking agent on morphology and the biocatalytic activity of the cells were examined. In the presence of an organic co-solvent, such as methanol or acetone (5%), the encapsulated Rhodococcus sp. AJ270 has been found to catalyze efficiently the biotransformation of racemic trans-2-methyl-3-phenyl-oxiranecarbonitrile and its amide to yield highly enantiopure 2R,3S-(-)-2-methyl-3-phenyl-oxiranecarboxamide in at least seven runs. (c) 2005 Elsevier Inc. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000237440200001 |
| 出版者 | ELSEVIER SCIENCE INC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/58979]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, MX |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Polymer Phys & Chem, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Biol Chem Lab, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, XL,Deng, G,Xu, J,et al. Immobilization of Rhodococcus sp AJ270 in alginate capsules and its application in enantio selective biotransformation of trans-2-methyl-3-phenyl-oxiranecarbonitrile and amide[J]. ENZYME AND MICROBIAL TECHNOLOGY,2006,39(1):1-5. |
| APA | Guo, XL,Deng, G,Xu, J,&Wang, MX.(2006).Immobilization of Rhodococcus sp AJ270 in alginate capsules and its application in enantio selective biotransformation of trans-2-methyl-3-phenyl-oxiranecarbonitrile and amide.ENZYME AND MICROBIAL TECHNOLOGY,39(1),1-5. |
| MLA | Guo, XL,et al."Immobilization of Rhodococcus sp AJ270 in alginate capsules and its application in enantio selective biotransformation of trans-2-methyl-3-phenyl-oxiranecarbonitrile and amide".ENZYME AND MICROBIAL TECHNOLOGY 39.1(2006):1-5. |
入库方式： OAI收割
来源：化学研究所
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