Alternating-electric-field-enhanced reversible switching of DNA nanocontainers with pH
文献类型：期刊论文
| 作者 | Mao, Youdong; Liu, Dongsheng; Wang, Shutao; Luo, Songnian; Wang, Wenxing; Yang, Yanlian; Qi Quyang; Lei Jiang |
| 刊名 | NUCLEIC ACIDS RESEARCH
 |
| 出版日期 | 2007 |
| 卷号 | 35期号:5 |
| ISSN号 | 0305-1048 |
| DOI | 10.1093/nar/gkl1161 |
| 英文摘要 | Macroscopically realizable applications of DNA-based molecular devices require individual molecules to cooperate with each other. However, molecular crowding usually introduces disorder to the system, thus jeopardizing the molecular cooperation and slowing down their functional performance dramatically. A challenge remaining in this field is to obtain both smarter response and better cooperation simultaneously. Here, we report a swift-switching DNA nanodevice that is enhanced by an alternating electric field. The device, self-assembled from folded four-stranded DNA motifs, can robustly switch between closed and open states in smart response to pH stimulus, of which the closed state forms a nanometer-height container that is impermeable to small molecules. This character was used to directly and non-specifically catch and release small molecules emulating mechanical hand in a controllable way. The alternating electric field was used to accelerate molecular cooperative motion during the device switching, which in turn shortened the closing time remarkably to thirty seconds. |
| 语种 | 英语 |
| WOS记录号 | WOS:000246371200036 |
| 出版者 | OXFORD UNIV PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/60319]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Dongsheng |
| 作者单位 | 1.Natl Ctr Nanosci & Technol, Beijing 100080, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China 3.Peking Univ, Dept Phys, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mao, Youdong,Liu, Dongsheng,Wang, Shutao,et al. Alternating-electric-field-enhanced reversible switching of DNA nanocontainers with pH[J]. NUCLEIC ACIDS RESEARCH,2007,35(5). |
| APA | Mao, Youdong.,Liu, Dongsheng.,Wang, Shutao.,Luo, Songnian.,Wang, Wenxing.,...&Lei Jiang.(2007).Alternating-electric-field-enhanced reversible switching of DNA nanocontainers with pH.NUCLEIC ACIDS RESEARCH,35(5). |
| MLA | Mao, Youdong,et al."Alternating-electric-field-enhanced reversible switching of DNA nanocontainers with pH".NUCLEIC ACIDS RESEARCH 35.5(2007). |
入库方式： OAI收割
来源：化学研究所
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