Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases
文献类型:期刊论文
作者 | Xu Yi-Zhuang; Zhao Ying; Ling Xiao-Feng; Yang Li-Min; Xu Zhi; Zhou Xiao-Si; Zhang Yuan-Fu; Gong Rong-Ye; Pan Qing-Hua; Wang Bing-Bing |
刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
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出版日期 | 2007-04-10 |
卷号 | 28期号:4页码:645-648 |
关键词 | Ftir Mid-ir Fiber Optics Gallbladder Detection |
ISSN号 | 0251-0790 |
英文摘要 | Identification of gallbladder cancer rapidly at the time of surgery would allow the appropriate resection to be completed at the original surgery. The aim of this study was to assess the sensitivity and specificity of FTIR in the rapid detection of gallbladder cancer, via an attenuated total reflection( ATR ) accessory with a ZnSe window. This allowed the edges of the surgically resected specimens to be examined rapidly. The results indicate that there are a series of differences between the spectra of normal and malignant tissues, and subtraction technique is helpful to identify cholecystitis and gallbladder cancer. Compared with pathological diagnosis results, one benign specimen was classified as a malignant and 6/6 malignant specimens and 39 cases of benign specimens were correctly classified. The sensitivity was 100% ( 6/6 ), specificity 97% ( 39/40 ), and accuracy was 97% ( 45/46 ). We can conclude that mid-infrared ATR FTIR spectroscopy is highly accurate and rapidly allows appropriately tailored resection at the time of initial surgery. |
语种 | 英语 |
WOS记录号 | WOS:000245874300010 |
出版者 | HIGHER EDUCATION PRESS |
源URL | [http://ir.iccas.ac.cn/handle/121111/60391] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Xu Yi-Zhuang |
作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, State Key Lab Rare Earth Mat & Applicat, Beijing 100871, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China 3.Peking Univ, Dept Surg, Hosp 3, Beijing 100083, Peoples R China 4.Beijing Rayleigh Analyt Instrument Corp, Beijing Opt Instrument Factory 2, Beijing 100015, Peoples R China 5.Xian Jiaotong Univ, Dept Surg Oncol, Hosp 1, Xian 710061, Peoples R China 6.Hangzhou Teachers Coll, Hangzhou 310015, Peoples R China 7.Second People Hosp Hangzhou, Hangzhou 310015, Peoples R China |
推荐引用方式 GB/T 7714 | Xu Yi-Zhuang,Zhao Ying,Ling Xiao-Feng,et al. Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2007,28(4):645-648. |
APA | Xu Yi-Zhuang.,Zhao Ying.,Ling Xiao-Feng.,Yang Li-Min.,Xu Zhi.,...&Wu Jin-Guang.(2007).Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,28(4),645-648. |
MLA | Xu Yi-Zhuang,et al."Fourier transform mid-infrared spectroscopy (FTIR) used for the rapid intraoperative diagnosis of gallbladder diseases".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 28.4(2007):645-648. |
入库方式: OAI收割
来源:化学研究所
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