Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems
文献类型：期刊论文
| 作者 | Chan, Sau Hing1; Lam, Kim Hung1; Li, Yue-Ming1; Xu, Lijin1; Tang, Weijun1; Lam, Fuk Loi1; Lo, Wai Hung1; Yu, Wing Yiu1; Fan, Qinghua2; Chan, Albert S. C.1 |
| 刊名 | TETRAHEDRON-ASYMMETRY
 |
| 出版日期 | 2007-11-12 |
| 卷号 | 18期号:22页码:2625-2631 |
| ISSN号 | 0957-4166 |
| DOI | 10.1016/j.tetasy.2007.10.034 |
| 英文摘要 | The iridium complex-catalyzed asymmetric hydrogenation of quinolines in a DMPEG/hexane biphasic system was studied. Catalysts with C-2-symmetric ligands such as Xyl-P-Phos, Cl-MeO-BIPHEP, SYNPHOS, and DiluorPhos are highly effective for this type of reaction. Most of the catalysts tested can be retained in DMPEG (M-n = 500), and the asymmetric hydrogenation of various quinoline substrates can be carried out in DMPEG/hexane biphasic system with up to 92% ee. The catalysts and the products can be separated via simple phase separation, and the reactivity/stereoselectivity of the catalysts can be retained for at least three reaction cycles. (c) 2007 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000251923900004 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/61395]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Chan, Albert S. C. |
| 作者单位 | 1.Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Open Lab Chirotechnol Inst Mol Technol Drug Disco, Hong Kong, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chan, Sau Hing,Lam, Kim Hung,Li, Yue-Ming,et al. Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems[J]. TETRAHEDRON-ASYMMETRY,2007,18(22):2625-2631. |
| APA | Chan, Sau Hing.,Lam, Kim Hung.,Li, Yue-Ming.,Xu, Lijin.,Tang, Weijun.,...&Chan, Albert S. C..(2007).Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems.TETRAHEDRON-ASYMMETRY,18(22),2625-2631. |
| MLA | Chan, Sau Hing,et al."Asymmetric hydrogenation of quinolines with recyclable and air-stable iridium catalyst systems".TETRAHEDRON-ASYMMETRY 18.22(2007):2625-2631. |
入库方式： OAI收割
来源：化学研究所
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