Synthesis of phosphinopeptides via the Mannich ligation
文献类型：期刊论文
| 作者 | Li, Bonan; Cai, Shuzong; Du, Da-Ming; Xu, Jiaxi |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2007-06-07 |
| 卷号 | 9期号:12页码:2257-2260 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/ol070360s |
| 英文摘要 | Phosphinopeptides are a class of unnatural peptides containing a tetrahedral phosphorus atom and have potential for use as enzyme inhibitors. A series of phosphinopeptides were synthesized via the Mannich-type reaction of aryldichlorophosphines, aldehydes, and N-protected amino amides or peptide amides and subsequent aminolysis with amino esters or peptide esters. The current method named the Mannich ligation is an efficient route to synthesis of phosphinopeptides through convergent condensation. |
| 语种 | 英语 |
| WOS记录号 | WOS:000246842600003 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/61597]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Xu, Jiaxi |
| 作者单位 | Peking Univ, Coll Chem & Mol Engn, Minist Educ, Key Lab Bioorgan Chem & Mol Engn,BNLMS, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Bonan,Cai, Shuzong,Du, Da-Ming,et al. Synthesis of phosphinopeptides via the Mannich ligation[J]. ORGANIC LETTERS,2007,9(12):2257-2260. |
| APA | Li, Bonan,Cai, Shuzong,Du, Da-Ming,&Xu, Jiaxi.(2007).Synthesis of phosphinopeptides via the Mannich ligation.ORGANIC LETTERS,9(12),2257-2260. |
| MLA | Li, Bonan,et al."Synthesis of phosphinopeptides via the Mannich ligation".ORGANIC LETTERS 9.12(2007):2257-2260. |
入库方式： OAI收割
来源：化学研究所
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