Preparation of molecularly imprinted monolith for trimethoprim molecule and its chromatographic property
文献类型：期刊论文
| 作者 | Liu Xiang-Jun; Liu Ji-Zhong; Zhao Rui; Liu Guo-Quan; Chen Yi |
| 刊名 | CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
 |
| 出版日期 | 2007-10-01 |
| 卷号 | 28期号:10页码:1878-1880 |
| 关键词 | Molecularly Imprinted Polymer Monolith Trimethoprim |
| ISSN号 | 0251-0790 |
| 英文摘要 | A monolithic molecularly imprinted polymer ( monolithic MIP) for trimethoprim ( TMP) was prepared by in situ polymerization method as the HPLC stationary phase. Methacrylic acid( MAA) and ethylene glycol dimethacrylate ( EDMA) were used as functional monomer and cross-linker, respectively. The obtained MIP monoliths were characterized by high performance liquid chromatography and scanning electron microscope. The SEM analysis result clearly shows that many macropores and flow-through pores were embedded in the network skeleton of the TMP-imprinted monolith, which allowed the mobile phase to flow through the monolithic MlPs with a very low flow resistance. When the flow rate was high to 9. 0 mL/min, the backpressure was only 11. 1 MPa. Moreover, the imprinting factor was up to 10. 3, which demonstrates that the obtained monolithic MIP showed a strong affinity and selectivity to the template molecule. |
| 语种 | 英语 |
| WOS记录号 | WOS:000250324400017 |
| 出版者 | HIGHER EDUCATION PRESS |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/61763]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao Rui |
| 作者单位 | Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu Xiang-Jun,Liu Ji-Zhong,Zhao Rui,et al. Preparation of molecularly imprinted monolith for trimethoprim molecule and its chromatographic property[J]. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,2007,28(10):1878-1880. |
| APA | Liu Xiang-Jun,Liu Ji-Zhong,Zhao Rui,Liu Guo-Quan,&Chen Yi.(2007).Preparation of molecularly imprinted monolith for trimethoprim molecule and its chromatographic property.CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE,28(10),1878-1880. |
| MLA | Liu Xiang-Jun,et al."Preparation of molecularly imprinted monolith for trimethoprim molecule and its chromatographic property".CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE 28.10(2007):1878-1880. |
入库方式： OAI收割
来源：化学研究所
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