Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor
文献类型:期刊论文
作者 | Han Xiao-Feng; Liu Yu-Xiu; Liu Ying; Lai Lu-Hua; Huang Run-Qiu; Wang Qing-Ming |
刊名 | CHINESE JOURNAL OF CHEMISTRY
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出版日期 | 2007-08-01 |
卷号 | 25期号:8页码:1135-1138 |
关键词 | 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates Hill Reaction Activity Photosystem Ii Electron Transport Inhibitor Binding Model 3d-qsar |
ISSN号 | 1001-604X |
英文摘要 | The binding model of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylate photosystem II (PSII) electron transport inhibitors with the D1 protein of PSII was built. The high herbicidal activity of this kind of inhibitors was explained by docking studies: in addition to usual factors, the N atom on the pyridine ring could form an H-bond with the backbone amide of Phe265 on the D1 protein. 3D-QSAR analysis on sixteen 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylate compounds was performed using CoMFA method to explain the nature of interactions between the compounds and D1 protein. These studies may provide useful insights for designing new PSII electron transport inhibitors. |
语种 | 英语 |
WOS记录号 | WOS:000248877900017 |
出版者 | WILEY-V C H VERLAG GMBH |
源URL | [http://ir.iccas.ac.cn/handle/121111/61785] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Liu Ying |
作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, State Key Lab Struct Chem Unstable & Stable Speci, BNLMS, Beijing 100871, Peoples R China 2.Peking Univ, Ctr Theoret Biol, Beijing 100871, Peoples R China 3.Nankai Univ, Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China |
推荐引用方式 GB/T 7714 | Han Xiao-Feng,Liu Yu-Xiu,Liu Ying,et al. Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor[J]. CHINESE JOURNAL OF CHEMISTRY,2007,25(8):1135-1138. |
APA | Han Xiao-Feng,Liu Yu-Xiu,Liu Ying,Lai Lu-Hua,Huang Run-Qiu,&Wang Qing-Ming.(2007).Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor.CHINESE JOURNAL OF CHEMISTRY,25(8),1135-1138. |
MLA | Han Xiao-Feng,et al."Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor".CHINESE JOURNAL OF CHEMISTRY 25.8(2007):1135-1138. |
入库方式: OAI收割
来源:化学研究所
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