中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor

文献类型:期刊论文

作者Han Xiao-Feng; Liu Yu-Xiu; Liu Ying; Lai Lu-Hua; Huang Run-Qiu; Wang Qing-Ming
刊名CHINESE JOURNAL OF CHEMISTRY
出版日期2007-08-01
卷号25期号:8页码:1135-1138
关键词3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates Hill Reaction Activity Photosystem Ii Electron Transport Inhibitor Binding Model 3d-qsar
ISSN号1001-604X
英文摘要The binding model of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylate photosystem II (PSII) electron transport inhibitors with the D1 protein of PSII was built. The high herbicidal activity of this kind of inhibitors was explained by docking studies: in addition to usual factors, the N atom on the pyridine ring could form an H-bond with the backbone amide of Phe265 on the D1 protein. 3D-QSAR analysis on sixteen 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylate compounds was performed using CoMFA method to explain the nature of interactions between the compounds and D1 protein. These studies may provide useful insights for designing new PSII electron transport inhibitors.
语种英语
WOS记录号WOS:000248877900017
出版者WILEY-V C H VERLAG GMBH
源URL[http://ir.iccas.ac.cn/handle/121111/61785]  
专题中国科学院化学研究所
通讯作者Liu Ying
作者单位1.Peking Univ, Coll Chem & Mol Engn, State Key Lab Struct Chem Unstable & Stable Speci, BNLMS, Beijing 100871, Peoples R China
2.Peking Univ, Ctr Theoret Biol, Beijing 100871, Peoples R China
3.Nankai Univ, Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
推荐引用方式
GB/T 7714
Han Xiao-Feng,Liu Yu-Xiu,Liu Ying,et al. Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor[J]. CHINESE JOURNAL OF CHEMISTRY,2007,25(8):1135-1138.
APA Han Xiao-Feng,Liu Yu-Xiu,Liu Ying,Lai Lu-Hua,Huang Run-Qiu,&Wang Qing-Ming.(2007).Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor.CHINESE JOURNAL OF CHEMISTRY,25(8),1135-1138.
MLA Han Xiao-Feng,et al."Binding model and 3D-QSAR of 3-(2-chloropyrid-5-ylmethylamino)-2-cyanoacrylates as PSII electron transport inhibitor".CHINESE JOURNAL OF CHEMISTRY 25.8(2007):1135-1138.

入库方式: OAI收割

来源:化学研究所

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