Formation and stability of G-quadruplexes self-assembled from guanine-rich strands
文献类型:期刊论文
作者 | Zhou, Jiang; Yuan, Gu; Liu, Junjun; Zhan, Chang-Guo |
刊名 | CHEMISTRY-A EUROPEAN JOURNAL
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出版日期 | 2007 |
卷号 | 13期号:3页码:945-949 |
关键词 | Dna G-quadruplexes Polyamides Self-assembly Telomeric Dna |
ISSN号 | 0947-6539 |
DOI | 10.1002/chem.200600424 |
英文摘要 | Electrospray ionization mass spectrometry (ESI-MS) was utilized to investigate the formation and stability of G-quadruplexes. For the 15 6-nt oligonucleotides tested, ESI-MS indicated that formation of a parallel tetramer quadruplex requires at least four continuous guanines in the 6-nt sequence. In addition, the G-rich strands prefer to employ "self- association" in the formation of the G-quadruplex rather than hybridized integration, and the thermodynamic-stability order of these three G-quadruplexes is Q(2) > Q(1) > Q(3). |
语种 | 英语 |
WOS记录号 | WOS:000243622500024 |
出版者 | WILEY-V C H VERLAG GMBH |
源URL | [http://ir.iccas.ac.cn/handle/121111/61891] ![]() |
专题 | 中国科学院化学研究所 |
通讯作者 | Yuan, Gu |
作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem,Beijing Natl Lab Mol Sci, Minist Educ,Key Lab Bioorgan Chem & Mol Engn, Beijing 100871, Peoples R China 2.Univ Kentucky, Coll Pharm, Dept Pharmaceut Sci, Lexington, KY 40536 USA |
推荐引用方式 GB/T 7714 | Zhou, Jiang,Yuan, Gu,Liu, Junjun,et al. Formation and stability of G-quadruplexes self-assembled from guanine-rich strands[J]. CHEMISTRY-A EUROPEAN JOURNAL,2007,13(3):945-949. |
APA | Zhou, Jiang,Yuan, Gu,Liu, Junjun,&Zhan, Chang-Guo.(2007).Formation and stability of G-quadruplexes self-assembled from guanine-rich strands.CHEMISTRY-A EUROPEAN JOURNAL,13(3),945-949. |
MLA | Zhou, Jiang,et al."Formation and stability of G-quadruplexes self-assembled from guanine-rich strands".CHEMISTRY-A EUROPEAN JOURNAL 13.3(2007):945-949. |
入库方式: OAI收割
来源:化学研究所
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