Radiation synthesis of PVP/CMC hydrogels as wound dressing
文献类型：期刊论文
| 作者 | Wang, Min1; Xu, Ling1; Hu, Hui1; Zhai, Maolin1; Peng, Jing1; Nho, Youngchang2; Li, Jiuqiang1; Wei, Genshuan1 |
| 刊名 | NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
 |
| 出版日期 | 2007-12-01 |
| 卷号 | 265期号:1页码:385-389 |
| 关键词 | Hydrogel Gamma-ray Irradiation Carboxymethyl Cellulose Poly(N-vinyl Pyrrolidone) Wound Dressing |
| ISSN号 | 0168-583X |
| DOI | 10.1016/j.nimb.2007.09.009 |
| 英文摘要 | Carboxymethyl cellulose (CMC) and poly(N-vinyl pyrrolidone) (PVP) were blended to synthesize hydrogels by (60)Co gamma-ray irradiation. A series of hydrogels were prepared with three. compositions, i.e. PVP:CMC = 5:5, 6:4 and 7:3. The properties of the hydrogels such as gel fraction, gel strength, swelling behavior and moisture retention were investigated. Compared with pure PVP and CIVIC hydrogels, PVP/CMC blend hydrogels possessed improved gel strength, flexibility and transparency. As the content of PVP in PVP/CMC blend hydrogels increased, the gel fraction increased while the swelling rate decreased. The hydrogels with optimal properties were obtained in a composition of PVP/CMC = 6/4 with sterilization dose (25 kGy) and further characterized by FT-IR and SEM. Properties concerning the application of wound dressing were performed by comparison with a commercial hydrogel wound dressing to find a similar moisture retention capability and improved swelling rate. The improved properties as well as the cheapness of the materials suggest that PVP/CMC blend hydrogel can be good candidate as wound dressing. (c) 2007 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000252025000074 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/61897]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhai, Maolin |
| 作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, Dept Appl Chem, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China 2.Korea Atom Energy Res Inst, Radiat Applicat Res Div, Seoul 580195, South Korea |
| 推荐引用方式 GB/T 7714 | Wang, Min,Xu, Ling,Hu, Hui,et al. Radiation synthesis of PVP/CMC hydrogels as wound dressing[J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,2007,265(1):385-389. |
| APA | Wang, Min.,Xu, Ling.,Hu, Hui.,Zhai, Maolin.,Peng, Jing.,...&Wei, Genshuan.(2007).Radiation synthesis of PVP/CMC hydrogels as wound dressing.NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS,265(1),385-389. |
| MLA | Wang, Min,et al."Radiation synthesis of PVP/CMC hydrogels as wound dressing".NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS 265.1(2007):385-389. |
入库方式： OAI收割
来源：化学研究所
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