A novel flavonoid from Lespedeza virgata (Thunb.) DC.: Structural elucidation and antioxidative activity
文献类型：期刊论文
| 作者 | Tan, Li; Zhang, Xiu-Feng; Yan, Bao-Zhen; Shi, Hai-Ming; Du, Li-Bo; Zhang, Ya-Zhou; Wang, Lan-Fen; Tang, Ya-Lin; Liu, Yang |
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2007-11-15 |
| 卷号 | 17期号:22页码:6311-6315 |
| 关键词 | Lespedeza Virgata Flavonoid Nmr Antioxidative Activity |
| ISSN号 | 0960-894X |
| DOI | 10.1016/j.bmcl.2007.09.003 |
| 英文摘要 | Bioactivity guided fractionation of the ethanolic extract of the whole plants of Lespedeza virgata (Thunb.) DC. resulted in the isolation of a novel flavonoid (1) along with five known compounds 2-6. The molecular and structural formula as well as the stereochemistry of compound 1 were determined using data obtained from (1)H and (13)C NMR spectra, DEPT135 and by 2D HSQC, HMBC, (1)H-(1)H correlated spectroscopy ((1)H-(1)H COSY), and nuclear overhauser effect spectroscopy (NOESY) experiments. The superoxide anion scavenging activities of all isolated compounds were evaluated by the hypoxanthine nitro blue tetrazolium and ESR methods and the new compound 1 showed the strongest antioxidative activity 95.79% (IC(50) = 0.14 mg/ml). (C) 2007 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000250906200054 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/62519]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Liu, Yang |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, State Key Lab SCUSS, Beijing 100080, Peoples R China 2.Beijing Univ Chem Technol, Fac Sci, Beijing 100029, Peoples R China 3.Peking Univ, Ctr Hlth Sci, Sch Pharmaceut Sci, Dept Nat Med, Beijing 100083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tan, Li,Zhang, Xiu-Feng,Yan, Bao-Zhen,et al. A novel flavonoid from Lespedeza virgata (Thunb.) DC.: Structural elucidation and antioxidative activity[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2007,17(22):6311-6315. |
| APA | Tan, Li.,Zhang, Xiu-Feng.,Yan, Bao-Zhen.,Shi, Hai-Ming.,Du, Li-Bo.,...&Liu, Yang.(2007).A novel flavonoid from Lespedeza virgata (Thunb.) DC.: Structural elucidation and antioxidative activity.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,17(22),6311-6315. |
| MLA | Tan, Li,et al."A novel flavonoid from Lespedeza virgata (Thunb.) DC.: Structural elucidation and antioxidative activity".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 17.22(2007):6311-6315. |
入库方式： OAI收割
来源：化学研究所
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