中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
DNA-mediated charge transport by minor groove-binding polyamide

文献类型:期刊论文

作者Ji, Zhonghua; Li, Jingjian; Zhu, Bin; Yuan, Gu; Cai, Shengmin
刊名ELECTROCHEMISTRY COMMUNICATIONS
出版日期2007-07-01
卷号9期号:7页码:1667-1671
关键词Polyamide Dna Minor Groove Charge Transport Broadened Pi-stack Human Telomere
ISSN号1388-2481
DOI10.1016/j.elecom.2007.03.020
英文摘要A novel polyamide-modified electrode was fabricated successfully by surface synthesis. The DNA-mediated charge transport by minor groove-binding polyamide was observed for the first time with a [Ru(NH3)(6)](2+/3+) probe. Two control experiments on HSC11H22NH2 SAM/Au electrode, with and without DNA adsorption, confirmed that polyamide-DNA complex was a medium of charge transport. Four different DNA sequences were employed to investigate the effect of the charge transport of the polyamide-DNA complex in the minor groove. The peak current and a positive shift of peak potential were enhanced with the affinity increase between polyamide and DNA sequences. The experimental result offers a powerful tool for exquisite recognition of different sequences of base-pairs in double-stranded DNA. (C) 2007 Elsevier B.V. All rights reserved.
语种英语
WOS记录号WOS:000248089400046
出版者ELSEVIER SCIENCE INC
源URL[http://ir.iccas.ac.cn/handle/121111/62567]  
专题中国科学院化学研究所
通讯作者Li, Jingjian
作者单位1.Peking Univ, Coll Chem & Mol Engn, Inst Chem Phys, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
2.Peking Univ, Minist Educ, Dept Biol Chem, Key Lab Bioinorgan Chem & Mol Engn, Beijing 100871, Peoples R China
推荐引用方式
GB/T 7714
Ji, Zhonghua,Li, Jingjian,Zhu, Bin,et al. DNA-mediated charge transport by minor groove-binding polyamide[J]. ELECTROCHEMISTRY COMMUNICATIONS,2007,9(7):1667-1671.
APA Ji, Zhonghua,Li, Jingjian,Zhu, Bin,Yuan, Gu,&Cai, Shengmin.(2007).DNA-mediated charge transport by minor groove-binding polyamide.ELECTROCHEMISTRY COMMUNICATIONS,9(7),1667-1671.
MLA Ji, Zhonghua,et al."DNA-mediated charge transport by minor groove-binding polyamide".ELECTROCHEMISTRY COMMUNICATIONS 9.7(2007):1667-1671.

入库方式: OAI收割

来源:化学研究所

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