MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue
文献类型：期刊论文
| 作者 | Ge, Guanglu; Han, Dong; Lin, Danying; Chu, Weiguo; Sun, Yunxu; Jiang, Lei; Ma, Wanyun; Wang, Chen |
| 刊名 | ULTRAMICROSCOPY
 |
| 出版日期 | 2007-04-01 |
| 卷号 | 107期号:4-5页码:299-307 |
| 关键词 | Atomic Force Microscopy Magnetic Ac Mode Astrocytes Arterial Intima Field Emission Scanning Electron Microscopy |
| ISSN号 | 0304-3991 |
| DOI | 10.1016/j.ultramic.2006.08.009 |
| 英文摘要 | Magnetic AC mode (MAC mode) atomic force microscopy (AFM), a novel type of tapping mode AFM in which the cantilever is driven directly by a magnetic field, is a powerful tool for imaging with high spatial resolution and better signal-to-noise in liquid environment. It may largely extend the application of AFM to living samples, especially those are sensitive to cantilever forces, even to multilayer tissue samples. However, there are few reports on the imaging of living cells by MAC mode AFM previously. In our present study, we explore the optimal imaging conditions of MAC mode AFM on living astrocytes and fresh arterial intima surface. We also used nude tips for PicoTREC panel (i.e., Aux in BNC, a new data collecting channel) to image living samples and discussed its difference with phase imaging. We show that living biological samples can be imaged by MAC mode AFM at details of comparable resolution as those by high resolution scanning electron microscopy. Furthermore, the combination of height, amplitude, phase and TREC panel signals provide abundant informations for the characteristics of living samples, such as topography, profile, stiffness and adhesion. (c) 2006 Elsevier B.V. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000244373700004 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/62917]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Han, Dong |
| 作者单位 | 1.Natl Ctr Nanosci & Technol, Beijing 100080, Peoples R China 2.Tsinghua Univ, Dept Phys, Beijing 100084, Peoples R China 3.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ge, Guanglu,Han, Dong,Lin, Danying,et al. MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue[J]. ULTRAMICROSCOPY,2007,107(4-5):299-307. |
| APA | Ge, Guanglu.,Han, Dong.,Lin, Danying.,Chu, Weiguo.,Sun, Yunxu.,...&Wang, Chen.(2007).MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue.ULTRAMICROSCOPY,107(4-5),299-307. |
| MLA | Ge, Guanglu,et al."MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue".ULTRAMICROSCOPY 107.4-5(2007):299-307. |
入库方式： OAI收割
来源：化学研究所
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