The effect of polymer architecture on the nano self-assemblies based on novel comb-shaped amphiphilic poly(allylamine)
文献类型：期刊论文
| 作者 | Thompson, Colin J.1; Ding, Caixia2; Qu, Xiaozhong2; Yang, Zhenzhong2; Uchegbu, Ijeoma F.3; Tetley, Laurence4; Cheng, Woei Ping1 |
| 刊名 | COLLOID AND POLYMER SCIENCE
 |
| 出版日期 | 2008-11-01 |
| 卷号 | 286期号:13页码:1511-1526 |
| 关键词 | Self-assembly Nanoparticles Micelle Amphiphilic Polymer |
| ISSN号 | 0303-402X |
| DOI | 10.1007/s00396-008-1925-8 |
| 英文摘要 | Twelve novel poly(allylamine) (PAA)-based, comb-shaped amphiphilic polymers have been developed. Hydrophobic groups of cetyl, palmitoyl and cholesteryl were randomly grafted to PAA and quaternisation was carried out on some modified polymers. Polymers were characterised using (1)H NMR, elemental analysis and differential scanning calorimetry. All polymers formed nano self-assemblies in the aqueous solution with a positive zeta potential and were able to encapsulate a hydrophobic agent, methyl orange, in the core. The critical aggregation concentration (CAC) and the microviscosity were found to be dependent on the polymer hydrophobicity. Being the most hydrophobic polymer, cholesteryl-grafted PAA had the lowest CAC (0.02 mg mL(-1)) and the highest microviscosity. They appeared to form dense nanoparticles and were transformed into novel nanostructures in the presence of free cholesterol. Palmitoyl-grafted polymers formed nanoparticles while cetyl-grafted polymers formed polymeric micelles. The flexibility of cetyl chains possibly resulted in the formation of multicore polymeric micelles. |
| 语种 | 英语 |
| WOS记录号 | WOS:000259720600007 |
| 出版者 | SPRINGER |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/63581]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Cheng, Woei Ping |
| 作者单位 | 1.Robert Gordon Univ, Sch Pharm & Life Sci, Aberdeen AB10 1FR, Scotland 2.Chinese Acad Sci, Inst Chem, State Key Lab Polymer Phys & Chem, Beijing 100190, Peoples R China 3.Univ London, Sch Pharm, London WC1N 1AX, England 4.Univ Glasgow, Integrated Microscopy Facil, Inst Biomed & Life Sci, Glasgow G12 8QQ, Lanark, Scotland |
| 推荐引用方式 GB/T 7714 | Thompson, Colin J.,Ding, Caixia,Qu, Xiaozhong,et al. The effect of polymer architecture on the nano self-assemblies based on novel comb-shaped amphiphilic poly(allylamine)[J]. COLLOID AND POLYMER SCIENCE,2008,286(13):1511-1526. |
| APA | Thompson, Colin J..,Ding, Caixia.,Qu, Xiaozhong.,Yang, Zhenzhong.,Uchegbu, Ijeoma F..,...&Cheng, Woei Ping.(2008).The effect of polymer architecture on the nano self-assemblies based on novel comb-shaped amphiphilic poly(allylamine).COLLOID AND POLYMER SCIENCE,286(13),1511-1526. |
| MLA | Thompson, Colin J.,et al."The effect of polymer architecture on the nano self-assemblies based on novel comb-shaped amphiphilic poly(allylamine)".COLLOID AND POLYMER SCIENCE 286.13(2008):1511-1526. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。