The use of glycolipids inserted in color-changeable polydiacetylene vesicles, as targets for biological recognition
文献类型：期刊论文
| 作者 | Boullanger, Paul1,2,3,4,5,6; Lafont, Dominique1,2,3,4,5,6; Bouchu, Marie-Noelle1,2,3,4,5,6; Jiang, Long7; Liu, Tao7; Lu, Wensheng7; Guo, Cai Xin7; Li, Jinru7 |
| 刊名 | COMPTES RENDUS CHIMIE
 |
| 出版日期 | 2008 |
| 卷号 | 11期号:1-2页码:43-60 |
| 关键词 | Polydiacetylene Monolayers Vesicles Glycolipids Color Change Recognition Biosensor |
| ISSN号 | 1631-0748 |
| DOI | 10.1016/j.crci.2007.03.007 |
| 英文摘要 | Topochemical organizations of conjugated diacetylenic acid photochemically polymerize to afford UV-visible absorbing polymers. Under the effect of an external stress caused by combination of the biomolecules to be recognized with the glycolipids on the vesicle surface, changes of conformation in the polymer backbone may result in a color change. Thus, monolayers and vesicles made of conjugated diacetylenic acid and a certain amount of glycolipids can be polymerized as far as the topochemical organization is not disrupted. In the presence of a protein (lectin, IgG, virus, etc.) or a microorganism (E. coli) able to bind with the glycolipid, the recognition at the interface resulted in a color change from blue to red. The synthesis of new glycolipids, and the study of their embedment into polydiacetylenic supramolecular assemblies allowed optimizing recognition parameters with regard to the structures of conjugated diynoic acids, the ideality of polydiacetylenic/glycolipidic mixtures, the polydiacetylene/glycolipid molar ratios, pH or vesicle sizes. The rapidity and the sensitivity of the phenomenon (often visible to the naked eye) together with the simplicity of its quantification (UV-visible spectrum) render it a good candidate for the development of biosensors. |
| 语种 | 英语 |
| WOS记录号 | WOS:000252801900007 |
| 出版者 | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/65545]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Boullanger, Paul |
| 作者单位 | 1.Inst Chim & Biochim Mol & Supramol, ICBMS, F-69622 Villeurbanne, France 2.CNRS, UMR 5246, F-69622 Villeurbanne, France 3.Univ Lyon, F-69622 Villeurbanne, France 4.Univ Lyon 1, F-69622 Villeurbanne, France 5.CPE Lyon, F-69622 Villeurbanne, France 6.INSA, F-69622 Villeurbanne, France 7.Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Key Lab Colloid & Interface Sci, Beijing 100080, Peoples R China |
| 推荐引用方式 GB/T 7714 | Boullanger, Paul,Lafont, Dominique,Bouchu, Marie-Noelle,et al. The use of glycolipids inserted in color-changeable polydiacetylene vesicles, as targets for biological recognition[J]. COMPTES RENDUS CHIMIE,2008,11(1-2):43-60. |
| APA | Boullanger, Paul.,Lafont, Dominique.,Bouchu, Marie-Noelle.,Jiang, Long.,Liu, Tao.,...&Li, Jinru.(2008).The use of glycolipids inserted in color-changeable polydiacetylene vesicles, as targets for biological recognition.COMPTES RENDUS CHIMIE,11(1-2),43-60. |
| MLA | Boullanger, Paul,et al."The use of glycolipids inserted in color-changeable polydiacetylene vesicles, as targets for biological recognition".COMPTES RENDUS CHIMIE 11.1-2(2008):43-60. |
入库方式： OAI收割
来源：化学研究所
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