Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice
文献类型：期刊论文
| 作者 | Yang, Sheng-Tao1; Wang, Haifang1,2; Meziani, Mohammed J.3,4; Liu, Yuanfang1,2; Wang, Xin3,4; Sun, Ya-Ping3,4 |
| 刊名 | BIOMACROMOLECULES
 |
| 出版日期 | 2009-07-01 |
| 卷号 | 10期号:7页码:2009-2012 |
| ISSN号 | 1525-7797 |
| DOI | 10.1021/bm900263z |
| 英文摘要 | Chemically modified carbon nanotubes with hydrophilic functionalities such as polyethylene glycols (PEGs) are widely pursued for potential biological and biomedical applications. In this study, PEGylated single-walled carbon nanotubes (PEG-SWNT) were intravenously administrated into mice to study their biodefunctionalization in vivo by using complementary Raman and photoluminescence measurements. There was meaningful defunctionalization of PEG-SWNT in liver over time, but not in spleen under similar conditions. The evidence from spectroscopic characterization and analyses is presented, and mechanistic implications are discussed. |
| 语种 | 英语 |
| WOS记录号 | WOS:000268139300043 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/66723]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Wang, Haifang |
| 作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China 2.Shanghai Univ, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China 3.Clemson Univ, Dept Chem, Clemson, SC 29634 USA 4.Clemson Univ, Lab Emerging Mat & Technol, Clemson, SC 29634 USA |
| 推荐引用方式 GB/T 7714 | Yang, Sheng-Tao,Wang, Haifang,Meziani, Mohammed J.,et al. Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice[J]. BIOMACROMOLECULES,2009,10(7):2009-2012. |
| APA | Yang, Sheng-Tao,Wang, Haifang,Meziani, Mohammed J.,Liu, Yuanfang,Wang, Xin,&Sun, Ya-Ping.(2009).Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice.BIOMACROMOLECULES,10(7),2009-2012. |
| MLA | Yang, Sheng-Tao,et al."Biodefunctionalization of Functionalized Single-Walled Carbon Nanotubes in Mice".BIOMACROMOLECULES 10.7(2009):2009-2012. |
入库方式： OAI收割
来源：化学研究所
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