中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes

文献类型:期刊论文

作者Wang, X.1; Jia, G.1; Wang, H.2; Nie, H.2; Yan, L.1; Deng, X. Y.3; Wang, S.1
刊名JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
出版日期2009-05-01
卷号9期号:5页码:3025-3033
关键词Cytotoxicity Alveolar Macrophages (Am) Diameter-effect Apoptosis Multi-walled Carbon Nanotubes (Mwnts)
ISSN号1533-4880
DOI10.1166/jnn.2009.025
英文摘要In this work, we focus on the diameter effects on cytotoxicity of different diametered multi-walled carbon nanotubes (MWNTs). Cellular viability, phagocytotic ability, and apoptosis of guinea pig alveolar macrophages (AM) exposed to MWNTs were studied. MWNTs in smaller diameter showed less cytotoxicity than the larger ones at the same dosage. The phagocytosis ability of AM was partially impaired when the concentration of MWNTs was up to 20 mu g/ml, where a further characteristic feature of AM apoptosis was observed. The results indicate that MWNTs in different diameters exhibited quite different cytotoxicity, and for the first time revealed the diameter-effect of MWNTs on cytotoxicity.
语种英语
WOS记录号WOS:000265186800033
出版者AMER SCIENTIFIC PUBLISHERS
源URL[http://ir.iccas.ac.cn/handle/121111/66809]  
专题中国科学院化学研究所
通讯作者Jia, G.
作者单位1.Peking Univ, Sch Publ Hlth, Dept Environm & Occupat Hlth, Beijing 100191, Peoples R China
2.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
3.Shanghai Univ, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China
推荐引用方式
GB/T 7714
Wang, X.,Jia, G.,Wang, H.,et al. Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2009,9(5):3025-3033.
APA Wang, X..,Jia, G..,Wang, H..,Nie, H..,Yan, L..,...&Wang, S..(2009).Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,9(5),3025-3033.
MLA Wang, X.,et al."Diameter Effects on Cytotoxicity of Multi-Walled Carbon Nanotubes".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 9.5(2009):3025-3033.

入库方式: OAI收割

来源:化学研究所

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