中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
The imide-dipeptides that show strong and stable beta-sheet-like interactions compared with natural sequence

文献类型:期刊论文

作者Ke, Damei1,2; Zhan, Chuanlang1; Li, Xiao1,2; Wang, Yaobing1,2; Li, Alexander D. Q.3; Yao, Jiannian1
刊名TETRAHEDRON LETTERS
出版日期2009-07-08
卷号50期号:27页码:3926-3928
ISSN号0040-4039
DOI10.1016/j.tetlet.2009.04.067
英文摘要In this Letter, we report solution behavior of two imide-dipeptides containing L-alanine and L-leucine residues. In contrast to natural sequence, the imide-dipeptidyl backbone contains distinct features: self-pairing H-bonds, topochemical symmetry, a peptide polindron sequence, and different orientations of side chains. The solution behavior in chloroform reveals that both the imide-dipeptides adopt beta-folding conformations and form beta-sheet-like assembly. Most surprisingly, they form more stable and stronger H-bonds than the natural counterpart, and thus show different H-bonding patterns from the natural sequence. (c) 2009 Elsevier Ltd. All rights reserved.
语种英语
WOS记录号WOS:000266890000050
出版者PERGAMON-ELSEVIER SCIENCE LTD
源URL[http://ir.iccas.ac.cn/handle/121111/67005]  
专题中国科学院化学研究所
通讯作者Zhan, Chuanlang
作者单位1.Chinese Acad Sci, Inst Chem, Lab Photochem, BNLMS, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Washington State Univ, Dept Chem, Pullman, WA 99164 USA
推荐引用方式
GB/T 7714
Ke, Damei,Zhan, Chuanlang,Li, Xiao,et al. The imide-dipeptides that show strong and stable beta-sheet-like interactions compared with natural sequence[J]. TETRAHEDRON LETTERS,2009,50(27):3926-3928.
APA Ke, Damei,Zhan, Chuanlang,Li, Xiao,Wang, Yaobing,Li, Alexander D. Q.,&Yao, Jiannian.(2009).The imide-dipeptides that show strong and stable beta-sheet-like interactions compared with natural sequence.TETRAHEDRON LETTERS,50(27),3926-3928.
MLA Ke, Damei,et al."The imide-dipeptides that show strong and stable beta-sheet-like interactions compared with natural sequence".TETRAHEDRON LETTERS 50.27(2009):3926-3928.

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来源:化学研究所

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