Assembly of environmental sensitive microcapsules of PNIPAAm and alginate acid and their application in drug release
文献类型：期刊论文
| 作者 | Wang, Anhe1; Tao, Cheng1; Cui, Yue1; Duan, Li1; Yang, Yang2; Li, Junbai1 |
| 刊名 | JOURNAL OF COLLOID AND INTERFACE SCIENCE
 |
| 出版日期 | 2009-04-15 |
| 卷号 | 332期号:2页码:271-279 |
| 关键词 | Microcapsules Thermoresponsive Ph-responsive Manganese Ions Drug Release |
| ISSN号 | 0021-9797 |
| DOI | 10.1016/j.jcis.2008.12.032 |
| 英文摘要 | The objective of this research was to fabricate stable and environmentally sensitive (PNIPAAm/ALG)(n) microcapsules via layer-by-layer (LbL) technique. The structure, thermosensitive and pH-sensitive properties of the microcapsules were characterized by transmission electron microscopy (TEM), confocal laser scanning microscopy (CLSM) and atomic force microscopy (AFM), individually. MnCO(3) microparticles and melamine formaldehyde (MF) microparticles were used as templates separately. The microcapsules from MnCO(3) cores were stable over a large pH range with thermosensitive and pH-sensitive properties, while those from MF particles were unstable in basic solutions. To the end, ALG and PNIPAAm were adsorbed on recrystallized taxol alternatively, which obviously prolonged the release time of taxol above lower crystal Solution temperature (LCST) of PNIPAAm. (c) 2008 Elsevier Inc. Ail rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000264257600001 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/67011]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Li, Junbai |
| 作者单位 | 1.Chinese Acad Sci, BNLMS, Int Joint Lab, Key Lab Colloid & Interface Sci,Inst Chem, Beijing 100190, Peoples R China 2.Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Anhe,Tao, Cheng,Cui, Yue,et al. Assembly of environmental sensitive microcapsules of PNIPAAm and alginate acid and their application in drug release[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE,2009,332(2):271-279. |
| APA | Wang, Anhe,Tao, Cheng,Cui, Yue,Duan, Li,Yang, Yang,&Li, Junbai.(2009).Assembly of environmental sensitive microcapsules of PNIPAAm and alginate acid and their application in drug release.JOURNAL OF COLLOID AND INTERFACE SCIENCE,332(2),271-279. |
| MLA | Wang, Anhe,et al."Assembly of environmental sensitive microcapsules of PNIPAAm and alginate acid and their application in drug release".JOURNAL OF COLLOID AND INTERFACE SCIENCE 332.2(2009):271-279. |
入库方式： OAI收割
来源：化学研究所
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