A Simple and Sensitive Biosensor Based on Silver Enhancement of Aptamer-Gold Nanoparticle Aggregation
文献类型：期刊论文
| 作者 | Zhang, Zhen; Chen, Chunlai; Zhao, Xin Sheng1 |
| 刊名 | ELECTROANALYSIS
 |
| 出版日期 | 2009-06-01 |
| 卷号 | 21期号:11页码:1316-1320 |
| 关键词 | Aptamers Gold Nanoparticles Adenosine Detection Biosensors Silver Enhancement |
| ISSN号 | 1040-0397 |
| DOI | 10.1002/elan.200804562 |
| 英文摘要 | We have found that dispersed gold nanoparticles (AuNPs) have higher silver enhancement than that of aggregated AuNPs. Based on this observation we propose a general methodology of assay, the silver enhancement of aptamer-gold nanoparticle aggregation (SEAGNA). The assay is simple, inexpensive, fast, and sensitive. Adenosine aptamer is used to demonstrate the essence of this method. A tiny amount of sample is enough, and 0.1 pmol (0.1 mu M in 1 mu L) of adenosine can be detected with naked eyes. The sensitivity of most existing AuNPs-based colorimetric biosensors can be easily improved by applying our silver enhancement. |
| 语种 | 英语 |
| WOS记录号 | WOS:000267235900014 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/67021]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Zhao, Xin Sheng |
| 作者单位 | 1.Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, State Key Lab Struct Chem Unstable & Stable Speci, Beijing 100871, Peoples R China 2.Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Zhen,Chen, Chunlai,Zhao, Xin Sheng. A Simple and Sensitive Biosensor Based on Silver Enhancement of Aptamer-Gold Nanoparticle Aggregation[J]. ELECTROANALYSIS,2009,21(11):1316-1320. |
| APA | Zhang, Zhen,Chen, Chunlai,&Zhao, Xin Sheng.(2009).A Simple and Sensitive Biosensor Based on Silver Enhancement of Aptamer-Gold Nanoparticle Aggregation.ELECTROANALYSIS,21(11),1316-1320. |
| MLA | Zhang, Zhen,et al."A Simple and Sensitive Biosensor Based on Silver Enhancement of Aptamer-Gold Nanoparticle Aggregation".ELECTROANALYSIS 21.11(2009):1316-1320. |
入库方式： OAI收割
来源：化学研究所
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