Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm
文献类型：期刊论文
| 作者 | Sun, Jing1,2; Chen, Xuesi1; Guo, Jinshan1,2; Shi, Quan1,2; Xie, Zhigang1,2; Jing, Xiabin1 |
| 刊名 | POLYMER
 |
| 出版日期 | 2009-01-16 |
| 卷号 | 50期号:2页码:455-461 |
| 关键词 | Biodegradable Nca Ring-opening Polymerization |
| ISSN号 | 0032-3861 |
| DOI | 10.1016/j.polymer.2008.11.015 |
| 英文摘要 | A novel biodegradable Y-shaped copolymer, poly(L-lactide)(2)-b-poly(gamma-benzyl-L-glutamic acid) (PLLA(2)-b-PBLG), was synthesized by the ring-opening polymerization (ROP) of N-carboxyanhydride of gamma-benzyl-L-glutamate (BLG-NCA) with centrally amino-functionalized poly(L-lactide), PLLA(2)-NH(2), as a macroinitiator in a convenient way. The Y-shaped copolymer and its precursors were characterized by (1)H NMR, FT-IR, GPC, WAXD and DSC measurements. The self-assembly of the PLLA(2)-b-PBLG copolymer in toluene and benzyl alcohol was examined. It was found that the self-assembly of the copolymer was dependent on solvent and on relative length of the PBLG block. For a copolymer with PLLA blocks of 26 in total degree of polymerization (DP), if the PBLG block was long enough (e.g., DP = 54 or more), the copolymer/toluene solution became a transparent gel at room temperature. In benzyl alcohol Solution, only PLLA(2)-b-PBLG containing ca. 190 BLG residues could form a gel: those with shorter PBLG blocks (e.g., DP = 54) became nano-scale fibrous aggregates and these aggregates were dispersed in benzyl alcohol homogeneously. Copolymers with short PBLG blocks behaved like a pure PLLA both in toluene and in benzyl alcohol. These experimental results were discussed and explained by virtue of the helical conformation of PBLG and the interactions between the solvents and the PLLA and/or PBLG segments. (C) 2008 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 |
| WOS记录号 | WOS:000262592400015 |
| 出版者 | ELSEVIER SCI LTD |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/67753]  |
| 专题 | 中国科学院化学研究所 |
| 通讯作者 | Jing, Xiabin |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Polymer Phys & Chem, Changchun Inst Appl Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Jing,Chen, Xuesi,Guo, Jinshan,et al. Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm[J]. POLYMER,2009,50(2):455-461. |
| APA | Sun, Jing,Chen, Xuesi,Guo, Jinshan,Shi, Quan,Xie, Zhigang,&Jing, Xiabin.(2009).Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm.POLYMER,50(2),455-461. |
| MLA | Sun, Jing,et al."Synthesis and self-assembly of a novel Y-shaped copolymer with a helical polypeptide arm".POLYMER 50.2(2009):455-461. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。